Table 4 Frequencies of SNPs and haplotypes in pfmdr1 and pfcrt genes over time
Year (N) | pfmdr1 | pfcrt | pfmdr1 + pfcrt | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
86Y | 1246Y | 86Y/1246Y | 76T | 86Y/76T | ||||||
N (%) | 95% CI | N (%) | 95% CI | N (%) | 95% CI | N (%) | 95% CI | N (%) | 95% CI | |
1999 (60) | 37 (61.6%) | 49.02–72.91 | 4 (6.6%) | 2.62–15.93 | 1 (1.6%) | 0.29–8.86 | 43 (71.6%) | 59.23–81.49 | 32 (53.3%) | 40.89–65.37 |
2001 (102) | 98 (96.1%) | 90.35–98.46 | 24 (23.5%) | 16.35–32.63 | 21 (20.5%) | 13.88–29.43 | 87 (85.3%) | 77.15–90.88 | 84 (82.3%) | 73.82–88.54 |
2004/5 (262) | 220 (83.9%) | 79.04–87.92 | 3 (1.1%) | 0.39–3.31 | 3 (1.1%) | 0.39–3.31 | 200 (76.3%) | 70.83–81.08 | 170 (64.8%) | 59.93–70.41 |
2006 (158) | 113 (71.5%) | 64.04–77.98 | 1 (0.6%) | 0.11–3.5 | 1 (0.6%) | 0.11–3.5 | 107 (67.7%) | 60.09–74.52 | 76 (48.1%) | 40.45–55.84 |
2011 (163) | 114 (69.9%) | 62.51–76.45 | 0 | 0–2.30 | 0 | 0–2.30 | 114 (69.9%) | 62.51–76.45 | 78 (47.8%) | 40.32–55.48 |
2013 (170) | 125 (73.5%) | 66.43–79.59 | 3 (1.7%) | 0.6–5.06 | 1 (0.6%) | 0.10–3.26 | 109 (64.1%) | 56.67–70.94 | 81 (47.6%) | 40.27–55.12 |
2016 (169) | 47 (27.8%) | 21.61–35 | 0 | 0–2.22 | 0 | 0–2.22 | 33 (19.5%) | 14.26–26.15 | 12 (7.1%) | 4.11–12 |
2019 (n139) | 19 (13.6%) | 8.93–20.36 | 0 | 0–2.29 | 0 | 0–2.29 | 4 (2.8%) | 1.12–7.17 | 0 | 0–2.29 |
p-value | 0 | 0 | 0 | 0 | 0 | |||||