Dynamic changes in genetic diversity, drug resistance mutations, and treatment outcomes of falciparum malaria from the low-transmission to the pre-elimination phase on the islands of São Tomé and Príncipe

Table 2 Factors correlated with log₁₀ parasite density (no. of observations = 7482)

Variables	Coefficient	SE	z value	p-value
Age	− 0.012	0.001	− 17.801	< 0.001
Male	0.011	0.022	0.516	0.606
Endemic season	0.033	0.022	1.474	0.141
Period B vs. D	0.393	0.031	12.490	< 0.001
Period C vs. D	0.404	0.028	14.319	< 0.001
Urban	− 0.139	0.070	− 1.984	0.050

Factors correlated with the levels of parasite density (log₁₀ transformed) are characterized using linear regression model. The definition of each variable is described in the method section. Parasite density in the low transmission periods (Period B and C, 2010–2013) are compared with that in the pre-elimination phase (Period D, 2014–2016) using dummy variables. Significant p-values (p < 0.05) are shown in italic

ISSN: 1475-2875