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Fig. 5 | Malaria Journal

Fig. 5

From: The presence of circulating antibody secreting cells and long-lived memory B cell responses to reticulocyte binding protein 1a in Plasmodium vivax patients

Fig. 5

Development and persistence of PvRBP1a-specific MBCs. PvRBP1a‐specific MBCs detected during acute malaria and after recovery. a The number of specific MBC responses to the PvRBP1a antigens, b tetanus toxoid (TT) in PBMCs from patients during acute malaria (n  = 10) and after recovery (1–3 months, n  = 7; 1–3 years, n  = 7) were determined by ELISPOT (with polyclonal activation). The frequency of MBCs is expressed per million cultured PBMCs. Each symbol represents the MBC number for one individual. c Statistical analysis of association between the responses of PvRBP1a‐specific MBCs and antibodies in 10, 7 and 7 patients at acute and recovered phases for 1–3 months and 1–3 years, respectively. The horizontal line represents mean values  ±  SEM. Dashed line indicates the cut‐off value

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Malaria Journal

ISSN: 1475-2875

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