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Table 2 Prevalence and prevalence ratios of moderate and severe nutritional outcomes in study children between study arms in Burkina Faso and Mali at the end of the malaria transmission season surveys (mITT population)

From: Impact of seasonal RTS,S/AS01E vaccination plus seasonal malaria chemoprevention on the nutritional status of children in Burkina Faso and Mali

 

Group

n/N(%)

Prevalence Ratio (95% CI) RTS,S alone or combined group vs. SMC alone

Prevalence Ratio (95% CI) combined vs. RTS,S alone

Wasteda

 2017

SMC alone

272/1679 (16.2)

Reference

 

RTS,S alone

301/1704 (17.7)

1.10 (0.95, 1.27)

Reference

Combined

239/1686 (14.2)

0.88 (0.75, 1.03)

0.80 (0.69, 0.94)

 2018

SMC alone

138/1631 (8.46)

Reference

 

RTS,S alone

146/1693 (8.62)

1.02 (0.82, 1.27)

Reference

Combined

112/1670 (6.71)

0.79 (0.62, 1.01)

0.78 (0.61, 0.99)

 2019

SMC alone

93/1600 (5.81)

Reference

 

RTS,S alone

117/1629 (7.18)

1.23 (0.95, 1.61)

Reference

Combined

106/1629 (6.51)

1.12 (0.85, 1.47)

0.91 (0.70, 1.17)

Severely wasted

 2017

SMC alone

100/1679 (5.96)

Reference

 

RTS,S alone

104/1704 (6.10)

1.04 (0.79, 1.35)

Reference

Combined

68/1686 (4.03)

0.68 (0.51, 0.92)

0.66 (0.49, 0.89)

 2018

SMC alone

28/1631 (1.72)

Reference

 

RTS,S alone

38/1693 (2.24)

1.30 (0.80, 2.11)

Reference

Combined

19/1670 (1.14)

0.66 (0.37, 1.18)

0.51 (0.29, 0.88)

 2019

SMC alone

20/1600 (1.25)

Reference

 

RTS,S alone

23/1629 (1.41)

1.12 (0.62, 2.03)

Reference

Combined

21/1629 (1.29)

1.03 (0.56, 1.89)

0.92 (0.51, 1.65)

Low MUAC-for-ageb

 2017

SMC alone

82/1706 (4.81)

Reference

 

RTS,S alone

98/1738 (5.64)

1.20 (0.90, 1.59)

Reference

Combined

82/1717 (4.78)

1.01 (0.75, 1.36)

0.84 (0.64, 1.12)

 2018

SMC alone

100/1653 (6.05)

Reference

 

RTS,S alone

110/1717 (6.41)

1.07 (0.82, 1.39)

Reference

Combined

89/1692 (5.26)

0.87 (0.66, 1.15)

0.81 (0.62, 1.06)

 2019

SMC alone

58/1617 (3.59)

Reference

 

RTS,S alone

76/1646 (4.62)

1.32 (0.95, 1.84)

Reference

Combined

72/1642 (4.38)

1.23 (0.88, 1.73)

0.93 (0.68, 1.28)

Very low MUAC-for-age

 2017

SMC alone

5/1706 (0.29)

Reference

 

RTS,S alone

13/1738 (0.75)

2.60 (0.93, 7.26)

Reference

Combined

8/1717 (0.47)

1.61 (0.53, 4.91)

0.62 (0.26, 1.49)

 2018

SMC alone

7/1653 (0.42)

Reference

 

RTS,S alone

10/1717 (0.58)

1.38 (0.53, 3.61)

Reference

Combined

3/1692 (0.18)

0.42 (0.11, 1.62)

0.30 (0.08, 1.10)

 2019

SMC alone

6/1617 (0.37)

Reference

 

RTS,S alone

2/1646 (0.12)

0.34 (0.07, 1.66)

Reference

Combined

8/1642 (0.49)

1.33 (0.46, 3.81)

3.94 (0.84, 18.5)

Underweightc

 2017

SMC alone

343/1702 (20.2)

Reference

 

RTS,S alone

357/1739 (20.5)

1.03 (0.90, 1.17)

Reference

Combined

339/1712 (19.8)

0.99 (0.87, 1.13)

0.96 (0.85, 1.10)

 2018

SMC alone

248/1648 (15.0)

Reference

 

RTS,S alone

286/1709 (16.7)

1.12 (0.96, 1.31)

Reference

Combined

263/1687 (15.6)

1.04 (0.88, 1.21)

0.93 (0.80, 1.08)

 2019

SMC alone

176/1611 (10.9)

Reference

 

RTS,S alone

201/1645 (12.2)

1.13 (0.93, 1.36)

Reference

Combined

193/1637 (11.8)

1.08 (0.89, 1.31)

0.96 (0.80, 1.16)

Severely underweight

 2017

SMC alone

109/1702 (6.40)

Reference

 

RTS,S alone

116/1739 (6.67)

1.05 (0.82, 1.35)

Reference

Combined

99/1712 (5.78)

0.91 (0.70, 1.19)

0.87 (0.67, 1.12)

 2018

SMC alone

52/1648 (3.16)

Reference

 

RTS,S alone

59/1709 (3.45)

1.10 (0.76, 1.58)

Reference

Combined

47/1687 (2.79)

0.88 (0.60, 1.30)

0.80 (0.55, 1.17)

 2019

SMC alone

26/1611 (1.61)

Reference

 

RTS,S alone

27/1645 (1.64)

1.03 (0.60, 1.75)

Reference

Combined

34/1637 (2.08)

1.29 (0.78, 2.14)

1.26 (0.76, 2.07)

Stuntedd

 2017

SMC alone

441/1701 (25.9)

Reference

 

RTS,S alone

437/1734 (25.2)

0.98 (0.87, 1.09)

Reference

Combined

448/1705 (26.3)

1.02 (0.91, 1.14)

1.04 (0.93, 1.17)

 2018

SMC alone

421/1645 (25.6)

Reference

 

RTS,S alone

414/1709 (24.2)

0.95 (0.85, 1.07)

Reference

Combined

449/1679 (26.7)

1.04 (0.93, 1.17)

1.10 (0.98, 1.23)

 2019

SMC alone

302/1606 (18.8)

Reference

 

RTS,S alone

317/1637 (19.4)

1.04 (0.90, 1.20)

Reference

Combined

321/1634 (19.6)

1.05 (0.91, 1.21)

1.01 (0.88, 1.16)

Severely stunted

 2017

SMC alone

145/1701 (8.52)

Reference

 

RTS,S alone

121/1734 (6.98)

0.82 (0.65, 1.03)

Reference

Combined

157/1705 (9.21)

1.08 (0.87, 1.34)

1.32 (1.05, 1.66)

 2018

SMC alone

102/1645 (6.20)

Reference

 

RTS,S alone

99/1709 (5.79)

0.94 (0.72, 1.23)

Reference

Combined

134/1679 (7.98)

1.29 (1.00, 1.65)

1.37 (1.07, 1.76)

 2019

SMC alone

69/1606 (4.30)

Reference

 

RTS,S alone

72/1637 (4.40)

1.04 (0.75, 1.43)

Reference

Combined

69/1634 (4.22)

0.99 (0.71, 1.37)

0.95 (0.69, 1.32)

  1. a WHZ data missing for 102 children in 2017, 73 in 2018, 54 in 2019
  2. bMUAC-for-age z-score data missing for 10 children in 2017, 5 in 2018, 7 in 2019
  3. cWAZ data missing for 18 children in 2017, 23 in 2018, 19 in 2019
  4. dHAZ data missing for 31 children in 2017, 34 in 2018, 35 in 2019