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Table 2 Genotypes and allelic frequency at ICAM-1- 29 loci

From: ICAM-1 Kilifi variant is not associated with cerebral and severe malaria pathogenesis in Beninese children

Clinical group

Genotype (n, %)

Frequency

K29/K29

K29/M29

M29/M29

K29

M29

Cerebral malaria (n = 74)

49 (66.2)

17 (23.0)

8 (10.8)

0.78

0.22

Severe non-cerebral malaria (n = 71)

40 (56.3)

18 (25.4)

13 (18.3)

0.69

0.31

Uncomplicated malaria (n = 70)

36 (51.4)

26 (37.1)

8 (11.4)

0.70

0.30

Total (n = 215)

125 (58.1)

61 (28.4)

29 (11.4)

0.72

0.27

  1. K29/K29 are wild-type homozygous patients; K29/M29 are heterozygous individuals; M29/M29 indicate homozygous patients with the ICAM-1Kilifi mutation. n, number of patients or samples