Table 7 Sensitivity and specificity of hospital malaria diagnosis based real time PCR
Real time PCR results as standard reference | Hospital laboratory Microscopic inspection of blood smear | Expert Microscopy results | ||
|---|---|---|---|---|
Positive | Negative | Positive | Negative | |
Positive PCR | 62 | 100 | 90 | 71 |
Negative PCR | 10 | 104 | 13 | 102 |
Sensitivity % (95%CI) | 38.3 (31.1, 45.9) | 55.9 (47.9, 63.6) | ||
Specificity % (95% CI) | 91.2 (84.6, 95.2) | 88.7 (81.1, 93.6) | ||
Positive predictive value % (95% CI) | 86.1 (76.3, 92.3) | 87.4 (79.0, 92.8) | ||
Negative predictive Value % (95% CI) | 51.0 (44.2, 57.8) | 59.0 (51.2, 66.3) | ||
Diagnostic accuracy % (95% CI) | 60.1 (54.1, 66.0) | 69.6 (58.1, 79.2) | ||
Agreement (Cohen's kappa) | 0.26 (0.18, 0.35) | 0.42 (0.32, 0.51) | ||