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Fig. 1 | Malaria Journal

Fig. 1

From: Genetic polymorphism of circumsporozoite protein of Plasmodium falciparum among Chinese migrant workers returning from Africa to Henan Province

Fig. 1

A Analysis of the N-terminal polymorphism of imported PfCSP in Henan Province. Dots represent the same residue as the 3D7 reference sequence. Dashes indicate intervals to maximize alignment. The yellow shaded area represents the predicted T-cell epitope area. The underlined conserved motif (KLKQP) was involved in the invasion of spores into mosquito salivary glands and bound to hepatocytes before invasion. The number of samples refers to the frequency of each haplotype. B Polymorphism characteristics of the central repeat region of imported PfCSP in Henan Province; 1: tetrapeptide motif NANP; 2: tetrapeptide motif NVDP; 3: tetrapeptide motif NPNP; 4: tetrapeptide motif NVDA; 1 and 2 represent known tetrapeptide repeats, and yellow shaded areas 3 and 4 represent newly discovered tetrapeptide motifs

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Malaria Journal

ISSN: 1475-2875

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