Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo

Table 5 Determinants of injectable antimalarial treatment for severe malaria at referral health facilities in community enrolments

Determinants	N	%	Adjusted OR	95% CI	p value
Age
Children (0–2 years)	921	61.0	Ref.
Children (2–5 years)	590	39.0	1.13	0.78–1.63	0.53
Enrolment location
CHW	40	2.7	Ref.
PHC	1471	97.4	0.57	0.17–1.91	0.36
Health Zone
Ipamu	716	47.4	Ref.
Kenge	500	33.1	6.30	3.30–12.05	< 0.001
Kingandu	295	19.5	0.83	0.48–1.44	0.51
Danger signs
No/Others	271	17.9	Ref.
Yes (iCCM general danger signs)	1049	69.4	1.12	0.70–1.78	0.64
Weakness or asthenia	68	4.5	1.16	0.45–2.98	0.76
Unable to sit	123	8.1	1.39	0.61–3.13	0.43
RAS administration
No	220	14.6	Ref.
Yes	1291	85.4	4.75	3.00–7.52	< 0.001
Referral delay
0–1 day	1066	70.6	Ref.
> 1 day/Not documented	445	29.4	1.05	0.71–1.55	0.81
Malaria test result (RHF)
Positive	1227	81.2	Ref.
Negative/Not done	284	18.8	0.07	0.04–0.11	< 0.001
Anaemia at arrival at RHF
No/mild anaemia/not done	726	48.1	Ref.
Severe anaemia (≤ 5 g/dL)	785	52.0	2.28	1.38–3.77	0.001
Other comorbidities
No	802	53.1	Ref.
Yes	709	46.9	2.36	1.62–3.44	< 0.001
Blood transfusion
Yes	775	51.29	Ref.
No	736	48.71	0.53	0.32–0.87	0.01

N = 1511. OR: Odds ratio; CHW: Community Health Worker; PHC: Primary Health Care; RHF: Referral Health Facilities; RAS: rectal artesunate; 95% CI: 95% confidence intervals

ISSN: 1475-2875