Skip to main content

Table 4 Univariate analysis of clinical malaria and its effects on anemia, iron deficiency, and soluble transferrin receptors among school aged children

From: Implication of asymptomatic and clinical Plasmodium falciparum infections on biomarkers of iron status among school-aged children in Malawi

Variables

Low Hb levels

Low ferritin concentration

High sTfR levels

OR

95% CI

P-value

OR

95% CI

P-value

OR

95% CI

P-value

Clinical malaria

 Positive

4.70

(3.04–7.27)

< 0.0001

1.49

(0.63–3.09)

0.4197

3.50

(2.41–5.08)

< 0.0001

 Negative

1.00

  

1.00

  

1.00

  

Sex

 Female

1.16

(0.77–1.75)

0.4782

1.65

(0.78–3.50)

0.1867

1.18

(0.83–1.69)

0.3628

 Male

1.00

  

1.00

  

1.00

  

Age

 5–10

2.14

(1.35–3.41)

0.0013

1.19

(0.56–2.51)

0.6507

1.00

(0.69–1.45)

0.9815

 11–14

1.00

  

1.00

  

1.00

  

Fever in last 2 weeks

 Yes

1.65

(1.04–2.65)

0.0342

1.26

(0.51–3.15)

0.6155

1.90

(1.26–2.87)

0.0023

 No

1.00

  

1.00

  

1.00

  

Diarrhea in last 2 weeks

 Yes

1.83

(0.80–4.20)

0.1535

1.70

(0.22–12.9)

0.6070

1.76

(0.84–3.69)

0.1359

 No

1.00

  

1.00

  

1.00

  

Elevated CRP or AGP

 Yes

4.00

(2.58–6.19)

< 0.0001

1.48

(0.65–3.39)

0.3506

1.93

(1.33–2.80)

0.0005

 No

1.00

  

1.00

  

1.00

  

Household hunger scale

 Little to none

0.78

(0.50–1.21)

0.2652

0.86

(0.41–1.80)

0.6970

0.84

(0.58–1.23)

0.3798

 Moderate to severe

1.00

  

1.00

  

1.00

  

Place of residence

 Urban

0.31

(0.12–0.78)

0.0125

0.97

(0.33–2.86)

0.9573

0.49

(0.25–0.99)

0.0482

 Rural

1.00

  

1.00

  

1.00

  

Geographical region

 Northern

0.87

(0.46–1.67)

0.6782

1.89

(0.76–4.66)

0.1674

0.82

(0.47–1.45)

0.5016

 Central

1.01

(0.54–1.90)

0.9806

1.82

(0.76–4.36)

0.1772

1.09

(0.63–1.88)

0.7616

 South

1.00

  

1.00

  

1.00

  
  1. Bold font indicates statistical significance
  2. CRP C-reactive protein, AGP Alpha-1-acid glycoprotein, Hb hemoglobin, sTfR soluble transferrin receptors, OR odds ratio, CI confidence interval