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Table 5 Multivariate analysis of asymptomatic malaria and its effect on anemia, iron deficiency, and soluble transferrin receptors among school aged children

From: Implication of asymptomatic and clinical Plasmodium falciparum infections on biomarkers of iron status among school-aged children in Malawi

Variables

Low Hb levels

Low Ferritin concentration

High sTfR levels

aOR

95% CI

P-value

aOR

95% CI

P-value

aOR

95% CI

P-value

Asymptomatic malaria

 Yes

3.71

(2.29–5.99)

< 0.0001

1.03

(0.44–2.37)

0.9491

3.00

(2.01–4.47)

< 0.0001

 No

1.00

  

1.00

  

1.00

  

Sex

 Female

1.02

(0.66–1.59)

0.9286

1.63

(0.77–3.46)

0.2057

1.11

(0.77–1.61)

0.5723

 Male

1.00

  

1.00

  

1.00

  

Age

 5–10

1.70

(1.03–2.79)

0.0378

1.11

(0.51–2.39)

0.7932

0.89

(0.61–1.32)

0.5746

 11–14

1.00

  

1.00

  

1.00

  

Fever in last 2 weeks

 Yes

1.08

(0.64–1.80)

0.7780

1.17

(0.46–3.01)

0.7428

1.62

(1.05–2.48)

0.0289

 No

1.00

  

1.00

  

1.00

  

Diarrhea in last 2 weeks

 Yes

1.32

(0.53–3.29)

0.5498

1.69

(0.22–13.2)

0.6157

1.39

(0.64–3.02)

0.4032

 No

1.00

  

1.00

  

1.00

  

Elevated CRP or AGP

 Yes

2.63

(1.64–4.24)

< 0.0001

1.33

(0.55–3.24)

0.5249

1.37

(0.91–2.05)

0.1344

 No

1.00

  

1.00

  

1.00

  

Household hunger scale

 Little to none

0.85

(0.53–1.38)

0.5122

0.81

(0.37–1.79)

0.6085

1.05

(0.70–1.58)

0.8028

 Moderate to severe

1.00

  

1.00

  

1.00

  

Place of residence

 Urban

0.53

(0.20–1.34)

0.1966

0.93

(0.29–2.99)

0.8995

0.73

(0.36–1.51)

0.3965

 Rural

1.00

  

1.00

  

1.00

  

Geographical region

 Northern

1.03

(0.53–1.97)

0.9379

2.04

(0.78–5.30)

0.1418

0.97

(0.56–1.69)

0.9114

 Central

0.85

(0.46–1.57)

0.5987

1.79

(0.74–4.31)

0.1974

1.11

(0.66–1.85)

0.7036

 South

1.00

  

1.00

  

1.00

  
  1. Bold font indicates statistical significance
  2. CRP C-reactive protein, AGP Alpha-1-acid glycoprotein, Hb hemoglobin, sTfR soluble transferrin receptors, aOR adjusted odds ratio, CI confidence interval