Table 5 Frequency of major epitopes in pfhrp2 and pfhrp3 exon-2 targeted by MAbs in HRP2-based RDT
MAb | Major epitope | Pfhrp2 | Pfhrp3 | ||
|---|---|---|---|---|---|
Frequency (%) | Median frequency (n) | Frequency (%) | Median frequency (n) | ||
3A4 | AHHAHHA | 100 | 14 | 70 | 1 |
2G12-1C12 | DAHHAADAHH | 99.06 | 4 | 0 | 0 |
1E1-A9 | AHHAHHV | 42.06 | 0 | 65 | 1 |
A6-4 | HATDAHH | 84.11 | 3 | 0 | 0 |
C1-13 | AHHAADAHH | 100 | 13 | 4 | 0 |
N7 | DAHHAADAHHA | 99.06 | 4 | 0 | 0 |
PTL-3 | YAHHAHHA | 95.33 | 2 | 0 | 0 |
S2-5 | AHHASDAHHA | 84.11 | 1 | 0 | 0 |
TC-10 | TDAHHAADAHHAADA | 54.21 | 1 | 0 | 0 |
C2-3 | HAHHAHHAADAHH | 43.93 | 0 | 0 | 0 |
Genway | AYAHHAHHAAY | 0 | 0 | 0 | 0 |