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Table 3 Secondary outcomes in patients with uncomplicated P. falciparum and P. vivax infections treated with AL or DHA/PPQ for P. falciparum, and CQ or DHA/PPQ for P. vivax, Ethiopia, 2017

From: Therapeutic efficacies of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum and chloroquine and dihydroartemisinin-piperaquine for uncomplicated Plasmodium vivax infection in Ethiopia

 

P. falciparum

P. vivax

AL

n = 102

DHA/PPQ

n = 74

CQ

n = 137

DHA/PPQ

n = 56

Proportion afebrile, n (%)

 Day 1

74 (73%)

70 (95%)

130 (95%)

53 (95%)

 Day 2

102 (100%)

74 (100%)

137 (100%)

56 (100%)

 Day 3

101 (100%)

74 (100%)

137 (100%)

56(100%)

Proportion parasite-clear, asexual, n (%)

 Day 2

97 (96%)

74 (100%)

137 (100%)

56 (100%)

 Day 3

100 (99%)

74 (100%)

137 (100%)

56 (100%)

Gametocyte carriage, n (%)

 Day 2

0 (0%)

1 (1%)

3 (2%)

0 (0%)

 Day 3

0 (0%)

0 (0%)

0 (0%)

0 (0%)

 Day 7

0 (0%)

0 (0%)

0 (0%)

0 (0%)

 Day 14

0 (0%)

0 (0%)

0 (0%)

0 (0%)

 Day 21

0 (0%)

0 (0%)

0 (0%)

0 (0%)

 Day 28

0 (0%)

0 (0%)

2 (2%)

0 (0%)

 Day 35

-

0 (0%)

–

0 (0%)

 Day 42

-

0 (0%)

–

0 (0%)

Mean Hb concentration, g/dl

 Day 0

14.0

13.8

12.75

14.0

 Day 14

12.5

12.7

13.0

13.6

 Day 28

12.7

13.2

13.2

14.4

 Day 42

-

14.3

–

14.5

  1. AL artemether-lumefantrine, DHA/PPQ dihydroartemisinin-piperaquine, CQ Chloroquine