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Table 3 Associations between P. vivax infection and being seropositive for antibodies to P. vivax antigens

From: Acquisition of antibodies to Plasmodium falciparum and Plasmodium vivax antigens in pregnant women living in a low malaria transmission area of Brazil

Antigen

P. vivax (%)

Uninfected (%)

AOR (95% CI)

P-value

PvMSP1-19

96.9

74.1

10.7 (3.2, 35.4)

< 0.0001

PvTRAg_2

84.4

25.4

15.7 (8.3, 29.7)

< 0.0001

PvTRAg_28

69.8

21.9

8.2 (4.7, 14.3)

< 0.0001

PvMSP8

79.2

29.4

9.3 (5.2, 16.7)

< 0.0001

PvMSP3

70.8

25.4

7.0 (4.1, 12.1)

< 0.0001

PVDBPII-Sal1

47.3

16.9

5.6 (3.2, 9.7)

< 0.0001

PvDBPII-AH

78.7

30.4

14.6 (7.6, 28.2)

< 0.0001

PvRAMA

90.6

42.8

12.8 (6.1, 27.0)

< 0.0001

RBP2b

79.2

38.8

6.2 (3.5, 11.0)

< 0.0001

PvEBPII

59.4

17.9

6.9 (4.0, 12.0)

< 0.0001

  1. Data presented as seropositivity percentage and odds ratio (95% confidence interval); Multivariate logistic regression analysis was performed to determine the effect of malaria infection on the antibody seropositivity in pregnant women with both P. falciparum and P. vivax infections and without plasmodium infection. Analysis was adjusted for gravidity, body mass index at enrolment, and maternal age enrollment. AOR, Adjusted odds ratio; 95% CI, 95% confidence interval; PV, Plasmodium vivax, RAMA, Rhoptry-associated membrane antigen; MSP, merozoite surface protein; PvTRAg, P. vivax tryptophan-rich antigen; PvEBP, P. vivax erythrocyte-binding protein; PvDBP II-sal1, P. vivax Duffy binding protein region II from ‘sal1’ strain; PvDBP II-AH, Duffy binding protein region II from ‘AH’ strain; RBP2b, reticulocyte binding protein 2b. P values that were less than 0.05 were designated in bold