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Table 7 Distribution of Pfcrt (N = 3), Pfmdr1 (N = 2), Pfdhfr (N = 13), Pfdhps (N = 26) haplotypes in four geographical regions of the state Odisha (period: 2018–2020)

From: Molecular surveillance of anti-malarial drug resistance genes in Plasmodium falciparum isolates in Odisha, India

Geographical regions

Northern Plateau

Central Table land

Coastal Belt

Eastern Ghat

Haplotypes

χ2

df

P-value

χ2

df

P-value

χ2

df

P-value

χ2

df

P-value

Pfcrt

            

CVMNK

15

12

0.241

15

12

0.241

15

12

0.241

15

12

0.241

CVIET

6

4

0.199

6

4

0.199

6

4

0.199

6

4

0.199

CVMNT

6

4

0.199

6

4

0.199

6

4

0.199

6

4

0.199

Pfmdr1

            

N86Y

6

4

0.199

6

4

0.199

6

4

0.199

6

4

0.199

Y184F

8

6

0.238

8

6

0.238

8

4

0.199

8

6

0.238

Pfdhfr

            

for 13 alleles

78

72

0.294

39

36

0.336

26

24

0.353

117

108

0.261

Pfdhps

            

for 26 alleles

130

125

0.326

78.000

75.000

0.384

78

75

0.384

182

175

0.343

  1. N number of haplotypes observed in the study, χ2 = Chi square test, df degree of freedom
  2. P-value =  < 0.05 significant