Table 1 Baseline demographic and clinical characteristics (randomized population)
Characteristic | Ferroquine 400 mg (N = 35) | Ferroquine 400 mg plus artefenomel | ||
|---|---|---|---|---|
300 mg (N = 36) | 600 mg (N = 36) | 1000 mg (N = 33) | ||
Age, years | 25.4 (13.2) | 21.8 (11.5) | 20.7 (8.6) | 22.2 (11.3) |
Female, n (%) | 23 (65.7) | 28 (77.8) | 26 (72.2) | 20 (60.6) |
Weight, kg | 57.8 (11.1) | 54.8 (10.0) | 54.9 (11.6) | 58.4 (12.1) |
BMI, kg/m2 | 21.1 (3.3) | 20.5 (3.6) | 20.6 (3.3) | 21.5 (4.0) |
Fever present, n (%) | 12 (34.3) | 16 (44.4) | 16 (44.4) | 16 (48.5) |
Parasitaemia, parasites/µL | 17,496 (11,890) [3188 to 46,076] | 18,800 (13,559) [3017 to 45,061] | 15,172 (13,013) [2848 to 54,141] | 20,547 (13,835) [3517 to 51,862] |
Parasitaemia, n (%) | ||||
< 3000, parasites/µL | 0 | 0 | 1 (2.8) | 0 |
3000–10,000, parasites/µL | 11 (31.4) | 14 (38.9) | 15 (41.7) | 11 (33.3) |
10,000–50,000, parasites/µL | 24 (68.6) | 22 (61.1) | 19 (52.8) | 21 (63.6) |
> 50,000, parasites/µL | 0 | 0 | 1 (2.8) | 1 (3.0) |