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Fig. 2 | Malaria Journal

Fig. 2

From: FT-GPI, a highly sensitive and accurate predictor of GPI-anchored proteins, reveals the composition and evolution of the GPI proteome in Plasmodium species

Fig. 2

Classifications of reference GPI-APs in Plasmodium falciparum and P. vivax by three tools: PredGPI, SignalP and TMPred. A. P. falciparum GPI-AP reference set from Gilson et al. [17] analysis. B. P. vivax GPI-AP reference set from Carlton et al. [38] analysis. Gene names are given in brackets. Members of the 6-cystein protein family are coloured in green, MSP proteins in blue, and ookinete P25 and P28 proteins in violet. Proteins with an internal TM score > 1200 are underlined. Italics indicate proteins with 0.6 < SignalP 5.0 score < 0.75. The three tools disagreed at times regarding the prediction of the cleavage site for these proteins (Additional file 1: Table S1). C-terminal TM’s detected with dend > 3 were labelled with *. A superscript label 2 indicated that the N-terminal TM was detected using the second ATG in ORF (a default option in FT-GPI)

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Malaria Journal

ISSN: 1475-2875

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