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Fig. 4 | Malaria Journal

Fig. 4

From: Metabolic responses in blood-stage malaria parasites associated with increased and decreased sensitivity to PfATP4 inhibitors

Fig. 4

Model-predicted rates of macromolecular syntheses in KAE609-treated and PA21A092-treated mutant parasites. A RNA synthesis. B Protein synthesis. C Polyamine synthesis. D Lipid synthesis. E Cofactor synthesis. F Inorganic ion generation. The error bars indicate one standard deviation (SD) of 20 simulations computed after adding random Gaussian noise with zero mean and a SD based on the respective transcriptomic data. g/h/gDW, grams per hour per gram dry weight of the parasite; MT + KA09, KAE609-treated P. falciparum Dd2A211V; MT + PA92, PA21A092-treated P. falciparum Dd2A211V; WT untreated P. falciparum Dd2

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