Table 4 In vivo anti-malarial activities of V. amygdalina leaf
From: A review of efficacy and safety of Ugandan anti-malarial plants with application of RITAM score
Efficacy (% suppression) | Plant collection site | Extract | Dose (mg/kg) | Route | Parasite strain | References |
|---|---|---|---|---|---|---|
73.9 | Uganda | Aq. | 200 | i.p | Plasmodium berghei | [61] |
32.47, 35.40, and 37.67% | Ethiopia | 80% methanolic extract | 200, 400 and 600 respectively | oral | P. berghei (ANKA strain) | [141] |
68.8, 69.3, 70.3% (suppression test, curative and prophylactic resp.) | Ethiopia | Aq. | 600 | Oral | P. berghei | [69] |
69.2, 70.8, and 71.5% (suppression test, curative and prophylactic resp.) | Ethiopia | Hydro-methanolic | 600 | Oral | P. berghei | [69] |
67.0% | Botwana | Ethanolic | 500 | NS | P. berghei | [142] |
63.92% and 75.13% | Uganda | Aq. | 200 and 400 respectively | Oral | Plasmodium berghei, Strain ANKA, MRA-311 | [66] |