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Table 3 Risk of bias of randomized controlled trial studies with ROB 2

From: Association of G6PD status and haemolytic anaemia in patients receiving anti-malarial agents: a systematic review and meta-analysis

Study

Randomization process

Deviation from intended interventions

Missing outcome data

Measurement of the outcome

Selection of reported result

Overall bias

Bastiaens et al. [19]

 +  + 

 + 

 +  +  + 

 + 

 + 

Some concerns

Tiono et al. [20]

 + 

 + 

 +  +  + 

 + 

 + 

Low risk

Dysoley et al. [21]

 + 

 +  + 

 +  +  + 

 + 

 + 

High risk

Tine et al. [22]

 + 

 + 

 + 

 + 

 + 

Low risk

Raman et al. [23]

 + 

 +  + 

 +  +  + 

 + 

 + 

Low risk

Leslie et al. [18]

 + 

 +  +  + 

 + 

 + 

 + 

High risk

Llanos-Cuentas et al. [15]

 + 

 + 

 + 

 + 

 + 

Low risk

Mwaiswelo et al. [24]

 + 

 + 

 + 

 + 

 + 

Low risk

Leslie et al. [14]

 +  +  + 

 + 

 + 

 + 

 + 

High risk

  1.  + : low risk, +  + : some concerns, +  +  + : high risk
  2. ROB 2 Cochrane risk-of-bias tool for randomized trials