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Table 3 Association of ATP2B4 SNPs with mild malaria in Senegalese population

From: ATP2B4 regulatory genetic variants are associated with mild malaria

 

Positiona

Minor allele

Risk genotype

Odd ratio

95% CI

P value

rs10751450 (C > T)

203681817

T

CC

3.55b (3.52)c

1.83–6.91b (1.78–6.95)c

0.0002b (0.0003)c

rs10751451 (C > T)

203681850

T

CC

3.35 (3.32)

1.72–6.51 (1.69–6.53)

0.0003 (0.0005)

rs10751452 (T > C)

203681902

C

TT

3.17 (3.13)

1.64–6.14 (1.60–6.15)

0.0006 (0.0009)

rs11240734 (T > C)

203682696

C

TT

3.42 (3.39)

1.76–6.64 (1.72–6.66)

0.0003 (0.0004)

rs1541252 (C > T)

203682799

T

CC

3.42 (3.39)

1.76–6.64 (1.72–6.66)

0.0003 (0.0004)

rs1541253 (C > T)

203682912

T

CC

3.42 (3.39)

1.76–6.64 (1.72–6.66)

0.0003 (0.0004)

rs1541254 (G > C)

203683012

C

GG

3.62 (3.60)

1.86–7.05 (1.83–7.10)

0.0001 (0.0002)

rs1541255 (A > G)

203683013

G

AA

3.62 (3. 60)

1.86–7.05 (1.83–7.10)

0.0001 (0.0002)

rs10900585(T > G)

203684896

G

TT

3.42b (3.39)c

1.76–6.6b (1.72–6.66)c

0.0003b (0.0004)c

  1. aData represent the position on chromosome 1 according to human hg38 coordinates
  2. bResults of the logistic regression analysis without any covariate
  3. cResults of the logistic regression analysis when taking into account age as a covariate