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Table 4 Clinical and biological features of severe falciparum malaria and relation to death of patient

From: Severe malaria in Gabon: epidemiological, clinical and laboratory features in Amissa Bongo Hospital of Franceville

Parameters

n

%

Died (n = 21)

Survived (n = 199)

p-value

Clinical parameters

 Prostration, n (%)

129

58.6

11 (8.53)

118 (91.47)

0.54

 Convulsions, n (%)

53

24.1

8 (15.09)

45 (84.91)

0.11

 Coma, n (%)

21

9.5

10 (47.62)

11 (52.38)

0.001

 Respiratory distress, n (%)

48

21.82

10 (20.83)

38 (79.17)

0.01

 Jaundice, n (%)

55

25

8 (14.55)

47 (85.45)

0.15

 Pulmonary oedema, n (%)

2/48**

4.17

0 (0)

2 (100)

–

 Macroscopic haemoglobinuria, n (%)

10

4.55

1 (10)

9 (90)

1

 Circulatory collapse, n (%)

3

1.36

1 (33.33)

2 (66.67)

–

 Anormal bleeding, n (%)

5

2.27

2 (40)

3 (60)

 < 0.01

Biological parameters

 Severe anaemia, n (%)

160

72.7

11 (6.88)

149 (93.12)

0.028

 Hyperparasitaemia, n (%)

12

5.45

2 (16.67)

10 (83.33)

0.31

 Hypoglycaemia, n (%)

7

3.18

4 (57.14)

3 (42.86)

 < 0.01

 Hyperbilirubin, n (%)

8/86*

9.3

   

 Hyperlactataemia, n (%)

59/108*

54.6

6 (10.17)

53 (89.83)

1

 Renal failure, n (%)

2/212*

0.94

2 (100)

0 (0)

–

  1. **X-ray were performed only in patients with evocative signs
  2. *Due to the availability of reagents, these exams were not performed in all patients