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Table 3 Diagnostic performance of malaria RDTs using qPCR as a reference method

From: Diagnostic performance of NxTek™ Eliminate Malaria-Pf test for the detection of Plasmodium falciparum in school children with asymptomatic malaria

Malaria diagnostic tools

qPCR

 + ve

-ve

Total

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI)

Kapa (95% CI)

Accuracy (95% CI)

hsRDT

 + ve

22

0

22

48.89 (33.70, 64.23)

100 (99.61, 100)

100 (85.00, 100)

70.51 (64.25, 76.09)

64 (51.00, 78.00)

74.4 (74.26, 79.58)

−ve

23

949

972

Total

45

949

994

cRDT

 + ve

22

0

22

48.89 (33.70, 64.23)

100 (99.61, 100)

100 (85.00, 100)

70.51 (64.25,76.09)

64 (51.00, 78.00)

74.4 (74.26, 79.58)

−ve

23

949

972

Total

45

949

994

Microscopy

 + ve

15

0

15

33.33 (20, 48)

100 (99.61, 100)

100 (79.60,100)

64.71 (59.86,69.27)

49 (33.00, 64.30)

66.7 (67.04,72.84)

−ve

30

949

979

Total

45

949

994

  1.  + ve positive, -ve negative, PPV positive predictive value, NPV negative predictive value
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Malaria Journal

ISSN: 1475-2875

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