Table 2 Presentation at emergency department
Variables | Malaria-PCR positive | Malaria-PCR negative | P value* |
|---|---|---|---|
Clinical findings | |||
GCS score on admission | 8 (7–9) | 8 (7–9) | 0.82 |
Number of signs of raised ICP | 2 (2–3) | 2 (2–3) | 0.12 |
Convulsions at ED (%) | 88/149 (59.1%) | 113/180 (62.8%) | 0.49 |
Capillary refill, seconds | 2 (2–3) | 3 (2–3) | 0.10 |
Focal neurological deficits (%) | 11/132 (8.3%) | 21/160 (13.1%) | 0.19 |
Infection focus outside CNS (%) | 8/134 (6.0%) | 32/161 (19.9%) | < 0.001 |
Clinically dehydrated (%) | 36/136 (26.5%) | 59/163 (36.2%) | 0.07 |
Clinically malnourished (%) | 28/138 (20.3%) | 52/165 (31.5%) | 0.03 |
Dyspnea at ED (%) | 94/136 (69.1%) | 117/163 (71.8%) | 0.62 |
Blood test results† | |||
Haemoglobin, g/L | 62 (51–81) | 82 (63–103) | < 0.001 |
Leukocyte count, x 10E9/L | 11.9 (7.6–15.5) | 11.0 (7.6–16.3) | 0.54 |
Polymorphonuclear leukocyte count, x 10E9/L | 6.6 (4.6–9.8) | 6.9 (4.2–9.8) | 0.92 |
Thrombocyte count, x 10E9/L | 73 (41–166) | 207 (95–360) | < 0.001 |
CRP, mg/L | > 160 (150– > 160) | 150 (55- > 160) | < 0.001 |
Glucose level, mmol/l | 4.6 (4.2–5.9) | 5.2 (4.2–6.7) | 0.04 |
CSF test results | |||
Leukocyte count, x 10E6/L | 0 (0–2) | 0 (0–2) | 0.26 |
Protein level, mg/dL | 60.7 (31.6–99.4) | 92.6 (48.8–157.6) | < 0.001 |
Glucose level, mmol/L | 3.8 (2.7–4.6) | 3.0 (1.7–4.4) | 0.02 |