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Table 3 Treatment and outcomes

From: PCR-confirmed malaria among children presenting with a decreased level of consciousness in Angola: a prospective, observational study

Variables

Malaria-PCR positive

Malaria-PCR negative

P value*

In-hospital treatment

 Blood transfusion (%)

89/130 (68.5%)

64/159 (40.3%)

 < 0.001

 Oxygen treatment (%)

116/135 (85.9%)

140/163 (85.9%)

0.99

 Malaria treatment (%)

135/139 (97.1%)

146/160 (91.3%)

0.03

 Quinine treatment (%)

75/137 (54.7%)

101/161 (62.7%)

0.16

 Anti-convulsives (%)

77/127 (60.6%)

115/156 (73.7%)

0.02

 Antibiotics (%)

86/132 (65.2%)

134/160 (83.8%)

 < 0.001

 Corticosteroids (%)

7/121 (5.8%)

36/155 (23.2%)

 < 0.001

 Acyclovir (%)

6/121 (5.0%)

32/155 (20.6%)

 < 0.001

 TB treatment (%)

0/136 (0.0%)

13/168 (7.7%)

 < 0.001

 Length of hospitalization, median days (IQR)

6 (4–9)

8 (5–13)

 < 0.001

Disease outcomes

 Death

37/148 (25%)

54/171 (31.6%)

0.19

 Day of death, median (IQR)

3 (2–4)

5 (3–9)

 < 0.001

 SeNeSe at discharge

3/102 (2.9%)

17/104 (16.3%)

0.001

 AnNeSe at discharge

5/97 (5.2%)

30/102 (29.4%)

 < 0.001

 Death or SeNeSe

40/139 (28.8%)

71/158 (44.9%)

0.004

  1. Data are presented as number of cases and percentages, unless otherwise specified
  2. AnNeSe any neurological sequelae; IQR interquartile range; SeNeSe severe neurological sequelae; TB tuberculosis
  3. *P values were obtained with Pearson’s chi-square test or the Mann–Whitney U test