Table 3 List of the mutations in the pfkelch13 gene previously observed in Senegal and in the present study
Plasmodium-specific/CCC/BTB-POZ | Propeller | Authors | Year(s) | City |
|---|---|---|---|---|
T149S and K189T* N142N/NN (insertion) | No mutation | Madamet et al. | 2012–2013 | Dakar |
D109H, L119L, H136N, P152P, M163I, K189T*, K189N, D214G, M235I, R239L, R255K, L258M, K278N, G287C, K293N, I313I, G357V, T367T, L368I, R398M, S423I, L429F | P443Q, S459S, Q468Q, C469C, C473F, W518C, G533V, R539I, R553I, V555L, E556V, P570L, A578D, R587I, G592V, R597I, A621A, A626V, W660C, G690G | Talundzic et al. | 2011–2014 | Dakar and Thiès |
K123R, N137S, N142NN/NNN, T149S, and K189T/N | N554H, Q613H, and V637I | Boussaroque et al. | 2013–2014 | Dakar |
D109H, T149S, K189N, K189T*, H274Y, D283Y, D389Y, N141-N142NN, N142N | T478T, A578S and V637I | Gaye et al. | 2015–2016 | Dakar (2015), Kédougou and Matam (2016) |
No mutation | C469C, F491F, G545G, F583F and A627A | Ahouidi et al. | 2015, 2016 and 2017 | Bounkiling |
No mutation | No mutation | Diallo et al. | 2018 | Diourbel and Kédougou |
No mutation | No mutation | Delandre et al. | 2015, 2016, 2017, 2018 and 2019 | Dakar |
K189T*, K248R | No mutation | This Study | 2017 | Thiès |