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Table 7 Distribution of the seven dhfr genotypes detected by site

From: Plasmodium falciparum drug resistance-associated mutations in isolates from children living in endemic areas of Burkina Faso

Genotype

Amino acid changes

N (%)

Sites

All sites

p-value

Banfora

Gaoua

Orodara

ACNCSI

Wild type

N

22

72

16

110

0.02

%

29.7%

29.8%

27.6%

29.4%

ACIRSI

51II/59R

N

41

119

36

196

%

55.4%

49.2%

62.1%

52.4%

ACIRNI

51I/59R/108N

N

4

44

3

51

%

5.4%

18.2%

5.2%

13.6%

ACNRSI

59R

N

6

3

2

11

%

8.1%

1.2%

3.4%

2.9%

ACNRNI

59R/108N

N

1

1

1

3

%

1.4%

0.4%

1.7%

0.8%

ACICSI

51I

N

0

2

0

2

%

0.0%

0.8%

0.0%

0.5%

ACNCNI

108N

N

0

1

0

1

%

0.0%

0.4%

0.0%

0.3%