Plasmodium falciparum drug resistance-associated mutations in isolates from children living in endemic areas of Burkina Faso

Table 9 Distribution of the 14 dhps genotypes detected per location

Genotype	Amino acid changes	N (%)	Sites			All site	p-value
Genotype	Amino acid changes	N (%)	Banfora	Gaoua	Orodara	All site	p-value
ISAKAA	Wild type	N	0	1	0	1	0.07
ISAKAA	Wild type	%	0.0%	0.4%	0.0%	0.3%
IAAKAA	436A	N	3	24	6	33
IAAKAA	436A	%	4.1%	9.9%	10.3%	8.8%
IFAKAA	436F	N	1	0	0	1
IFAKAA	436F	%	1.4%	0.0%	0.0%	0.3%
ISKKAA	437 K	N	39	72	28	139
ISKKAA	437 K	%	52.7%	29.8%	48.3%	37.2%
IAKKAA	436A/437 K	N	23	99	19	141
IAKKAA	436A/437 K	%	31.1%	40.9%	32.8%	37.7%
IAAKAS	436A/613S	N	1	3	0	4
IAAKAS	436A/613S	%	1.4%	1.2%	0.0%	1.1%
IYAKAS	436Y/613S	N	1	0	0	1
IYAKAS	436Y/613S	%	1.4%	0,0%	0.0%	0.3%
ISKKAS	437 K/613S	N	0	2	0	2
ISKKAS	437 K/613S	%	0.0%	0.8%	0.0%	0.5%
ISKKGA	437 K/581G	N	0	1	0	1
ISKKGA	437 K/581G	%	0.0%	0.4%	0.0%	0.3%
IAKKAS	436A/437 K/613S	N	6	36	4	46
IAKKAS	436A/437 K/613S	%	8.1%	14.9%	6.9%	12.3%
IAKEAA	436A/437 K/540E	N	0	1	0	1
IAKEAA	436A/437 K/540E	%	0.0%	0.4%	0.0%	0.3%
VAKKAA	431 V/436A/437 K	N	0	1	0	1
VAKKAA	431 V/436A/437 K	%	0,0%	0.4%	0.0%	0.3%
VAKKGA	431 V/436A/437 K/581G	N	0	2	0	2
VAKKGA	431 V/436A/437 K/581G	%	0.0%	0.8%	0.0%	0.5%
VAKKAS	431 V/436A/437 K/613S	N	0	0	1	1
VAKKAS	431 V/436A/437 K/613S	%	0.0%	0.0%	1.7%	0.3%

ISSN: 1475-2875