Fig. 1

Profile of pro-inflammatory cytokines during the course of the various disease conditions. Scatter plot graphs are plotted showing the concentrations (pg/ml) of A–F IL-1β, IL-6, IL-2, IL-12, IL-17A, GM-CSF and median fluorescence intensities (MFI) of G–V Eotaxin, IFN-γ, RANTES, MCP-1, IL-15, IL-5, IL-1RA, IL-2R, IFN-α, IP-10, TNF, MIG, MIP-1α, MIP-1β, IL-7 and IL-8 in plasma samples collected from uninfected controls (n = 20), patients with severe malaria (n = 27) and uncomplicated malaria (n = 10). For each figure, the interquartile ranges (IQR) are shown as vertical bars and the median is shown as horizontal bars. Significant differences are denoted by *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns not significant