Advances in the genetic characterization of the malaria vector, Anopheles funestus, and implications for improved surveillance and control

Table 2 Selected genes involved in insecticide resistance in An. funestus and their geographical distribution across Africa

Geographical distribution	Insecticide class	Resistance mechanism	Resistance genes	References
Southern Africa	Pyrethroid	Metabolic	CYP6P9a, CYP6M7, and CYP6P9b	[31, 91]
Eastern Africa	Pyrethroid	Metabolic	CYP6M4, CYP9K1, CYP6P9b, CYP304b1, CYP6M7, CYP6N1, CYP6M1, and CYP6Z1	[93,94,95]
West Africa	Pyrethroid and Organochloride	Metabolic	CYP6P9a, CYP6P9b, and GSTe2	[97,98,99]
Central, South and West Africa	Organochloride	Metabolic and target-site	CYP6P9a/b, A296S RDL, and GSTe2	[99, 100]

ISSN: 1475-2875