Efficacy of the spatial repellent product Mosquito Shield™ against wild pyrethroid-resistant Anopheles arabiensis in south-eastern Tanzania

Table 1 Summary statistics and indoor protective efficacy of Mosquito Shield™ in reducing human landings and blood-feeding of wild pyrethroid-resistant An. arabiensis

Experiment	Intervention	¹Total captured	²William’s Mean (95% CI)	³IRR (95% CI)	⁴PE (95% CI)	p-value
HLC	Control	16,392	53.8 (50.0, 57.8)	–	–	< 0.0001
HLC	Mosquito Shield™	5591	14.8 (13.2, 16.7)	0.30 (0.22, 0.43)	70 (57, 78)	< 0.0001
Feeding	Control	195	2.0 (1.7, 2.2)	–	–	< 0.0001
Feeding	Mosquito Shield™	61	1.5 (1.2, 1.7)	0.31 (0.21, 0.44)	69 (56, 79)	< 0.0001
Resting	Control	48	0.24 (0.15, 0.33)	–	–	P = 0.001
Resting	Mosquito Shield™	21	0.11 (0.06, 0.17)	0.39 (0.22, 0.68)	61 (32, 78)	P = 0.001

¹Total captured refers total number of An. arabiensis that landed on participants during the HLC experiment and total number of blood-fed collected from the feeding experiment; ²Average caught per night per hut estimated as geometric mean due to skewness of mosquito count data; ³Incidence rate ratio (IRR) for intervention is reported from generalized negative binomial mixed effect model of mosquito landings/blood-fed adjusted for the effect of volunteer, hut location and study night. ⁴PE = Protective efficacy ((1-IRR) * 100); for landing inhibition is the percentage reduction in mosquito lands while for blood-feeding inhibition is the percentage reduction in number of blood-fed mosquitoes in the intervention relative to the control

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