Association of apoptosis-related variants to malaria infection and parasite density in individuals from the Brazilian Amazon

Table 1 Characterization of the INDEL variants included in the panel

Genes	ID	Region	Alleles	MAF	Primers	Amplicon size
FAS	rs10532972	Intron	TTC/-	0.12	F5’GCATCAGGACGCTGAACATA3’ R5’AATGCAACTTGCTCCAGAGG3’	368–371
FADD	rs4197	3’-UTR	-/TGT	0.47	F 5’TGCCCCTACTTAGCAGTCTCA3’ R 5’GAGAGGTGGAGAACTGGGATT3’	278–281
CASP8	rs3834129	Promoter	AGTAAG/-	0.39	F 5’CTCTTCAATGCTTCCTTGAGGT3’ R 5’CTGCATGCCAGGAGCTAAGTAT3’	249–255
CASP8	rs59308963	Intron	ATTCTGTC/-	0.26	F 5’TTTTTGTCCTCCAAGCTTCC3’ R 5’GAACAAGAGAGAGGGCAGGA3’	261–269
CASP9	rs61079693	Intron	AAAA/-	0.32	F 5’CATGCACAGCTATCCAGGAG3’ R 5’TTGTTCCTGTCCGATAGATGC3’	458–462
CASP3	rs4647655	Intron	-/AAATCCTGAA	0.28	F 5’AGGAGTATCCCCTCGTGGAC3’ R 5’CAAGAGTCAGGCAAAAACAGG3’	379–389
BCL-2	rs11269260	Intron	TCTATCACCGATCATT/-	0.37	F 5’GCTTCCAGTTCCATCCATGT3’ R 5’CTCAGCGTGGTAGTGTTGGA3’	189–205
TP53	rs17880560	3’-Flanking	-/GCCGTG	0.21	F 5’CTGTGTGTCTGAGGGGTGAA3’ R 5’ATCCTGCCACTTTCTGATGG3’	400–406

ISSN: 1475-2875