Table 4 Comparison of the genotypic distribution of the P. vivax-malaria and control group (CG)
Genotype | Pva (%) | CGb (%) | P-valuec | OR (95% CI)d | OR (95% CI)e |
|---|---|---|---|---|---|
FAS (rs10562972) | |||||
DEL/DEL | 1 (3.8) | 1 (0.9) | 0.996 | 1.000 (0.000-∞) | 1.051 (0.000-∞) |
INS/DEL | 1 (3.8) | 24 (23.7) | |||
INS/INS | 24 (92.4) | 76 (75.4) | 0.143 | 2.267 (0.455–5.109) | 1.801 (0.860–4.259) |
FADD (rs4197) | |||||
DEL/DEL | 10 (38.5) | 45 (44.6) | 0.457 | 0.855 (0.492–1.473) | 0.802 (0.446–1.426) |
INS/DEL | 13 (50.0) | 48 (47.5) | |||
INS/INS | 3 (11.5) | 8 (7.9) | 0.365 | 1.169 (0.679–2.032) | 1.420 (0.636–3.020) |
CASP8 (rs3834129) | |||||
DEL/DEL | 5 (19.2) | 19 (18.8) | 0.818 | 1.015 (0.534–1.675) | 0.923 (0.458–1.780) |
INS/DEL | 14 (53.9) | 43 (42.6) | |||
INS/INS | 7 (26.9) | 39 (38.6) | 0.099 | 0.985 (0.536–1.870) | 0.594 (0.312–1.095) |
CASP8 (rs59308963) | |||||
DEL/DEL | 7 (26.9) | 29 (28.7) | 0.805 | 0.947 (0.526–1.670) | 0.925 (0.492–1.699) |
INS/DEL | 16 (61.6) | 53 (52.5) | |||
INS/INS | 3 (11.5) | 19 (18.8) | 0.142 | 1.055 (0.597–1.901) | 0.551 (0.229–1.165) |
CASP9 (rs61079693) | |||||
DEL/DEL | 5 (19.2) | 33 (32.7) | 0.311 | 0.657 (0.349–1.189) | 0.720 (0.375–1.338) |
INS/DEL | 18 (69.3) | 44 (43.6) | |||
INS/INS | 3 (11.5) | 24 (23.7) | 0.329 | 1.522 (0.841–2.860) | 0.701 (0.330–1.390) |
CASP3 (rs4647655) | |||||
DEL/DEL | 17 (65.4) | 51 (50.5) | 0.176 | 1.466 (0.848–2.571) | 1.499 (0.840–2.710) |
INS/DEL | 7 (26.9) | 40 (39.6) | |||
INS/INS | 2 (7.7) | 10 (9.9) | 0.702 | 0.682 (0.389–1.178) | 0.853 (0.360–1.822) |
BCL2 (rs11269260) | |||||
DEL/DEL | 8 (30.8) | 19 (18.8) | 0.167 | 1.466 (0.813–2.597) | 1.532 (0.828–2.800) |
INS/DEL | 11 (42.3) | 45 (44.6) | |||
INS/INS | 7 (26.9) | 37 (36.6) | 0.233 | 0.682 (0.385–1.230) | 0.688 (0.368–1.254) |
TP53 (rs17880560) | |||||
DEL/DEL | 20 (77.0) | 63 (62.4) | 0.271 | 1.524 (0.856–2.786) | 1.409 (0.773–2.634) |
INS/DEL | 5 (19.2) | 34 (33.7) | |||
INS/INS | 1 (3.8) | 4 (3.9) | 0.909 | 0.656 (0.359–1.167) | 1.063 (0.324–2.768) |