Seasonal malaria chemoprevention in a context of high presumed sulfadoxine-pyrimethamine resistance: malaria morbidity and molecular drug resistance profiles in South Sudan

Table 2 Uncomplicated malaria incidence and percentual reduction in two different age groups in the intervention area (Incidence per100)

SMC Cycle	Weeks	Under five years of age				5–14 years of age
SMC Cycle	Weeks	Incidence per 100	Estimate	IRR	Percent reduction	Incidence per 100	Estimate	IRR	Percent reduction
0	26–29	6.62	Ref	1		5.26	Ref	1
1	30–33	3.43	− 0.65*	0.52	48%	3.72	− 0.43*	0.71	29%
2	34–37	2.47	− 0.98*	0.37	63%	3.41	− 0.60*	0.65	35%
3	38–43	3.64	− 0.59*	0.55	45%	4.50	− 0.33*	0.86	14%
4	44–48	4.06	− 0.48*	0.61	49%	4.98	− 0.25*	0.95	5%
5	49–52	2.74	− 0.88*	0.41	59%	3.56	− 0.56	0.68	32%

Weeks represents epidemiological weeks. I: Incidence of uncomplicated malaria cases per 100 people by SMC cycle, the denominator was calculated according to estimated percentage of each age group (18.74% under five, 25.52% 5–14 years), total population was estimated to be 109,435 people. Estimate according to Poisson model (malaria cases ~ SMC cycle standardized by age group). IRR: Incidence rate ratio. Percent reduction: percentage of reduction in malaria incidence compare to period 0. *: p-value < 0.001

ISSN: 1475-2875