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Fig. 4 | Malaria Journal

Fig. 4

From: Comparative analyses of functional antibody-mediated inhibition with anti-circumsporozoite monoclonal antibodies against transgenic Plasmodium berghei

Fig. 4

Correlation between in vitro and in vivo inhibition of anti-CSP monoclonal antibodies. Inhibition percentage normalized to control for relative luminescence between in vitro and in vivo assays of a PbmCh-luc and b Pb-PfCSP(r) at 250, 125, and 25 µg/ml concentrations of anti-CSP 3D11 and 2A10 respectively. Correlation was tested using Spearman’s r test in Prism (GraphPad, La Jolla, CA, USA) with r and p-values in text. ‘*’ indicates this in vivo dilution represents 4 technical replicates. Results are represented as median ± 95% CI

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Malaria Journal

ISSN: 1475-2875

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