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Fig. 4 | Malaria Journal

Fig. 4

From: Evaluation of a new fusion antigen, cd loop and HAP2-GCS1 domain (cd-HAP) of Plasmodium falciparum Generative Cell Specific 1 antigen formulated with various adjuvants, as a transmission blocking vaccine

Fig. 4

Analysis of anti-cd-HAP IgG subclasses profiles, persistence and evaluation the Th1/Th2 ratios. A The profile of anti- cd-HAP IgG subclasses among vaccinated mouse groups for 9 individual mice (day 38) and 3 individual mice (day 180) in each group, respectively. The bars and error bars show the mean OD450 values and standard deviations (SD). B, C the Th1/Th2 ratio was calculated for each group on day 38 after the first immunization. One-way ANOVA analysis showed significant mean difference for the level of anti-cd-HAP IgG1, IgG2a, IgG2b, and IgG3 antibodies between vaccine groups 1–5 (P < 0.0001). D The Table shows multiple comparisons of means performed by Bonferroni post hoc test for anti-cd-HAP IgG subclasses among vaccine groups on day 38 after primary immunization

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Malaria Journal

ISSN: 1475-2875

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