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Table 3 Logistic regression analysis of the various factors associated with the different anti-malarial markers from the study sites

From: Assessment of Plasmodium falciparum drug resistance associated molecular markers in Mandla, Madhya Pradesh, India

Factors

Pfdhfr

Pfdhps

Pfmdr1

n/d (%)

OR (95% CI)

n/d (%)

OR (95% CI)

n/d (%)

OR (95% CI)

Endemicity

 Low

12/19 (63.16)

Reference

17/17 (100)

Reference

4/11 (36.36)

Reference

 Moderate

30/65 (46.15)

0.50 (0.17–1.43)

77/77 (100)

Empty

27/47 (57.45)

2.26 (0.61–9.18)

 High

73/115 (63.48)

1.10 (0.37–2.77)

105/121 (86.78)

Omitted

60/83 (72.29)

4.56 (1.22–17.07)*

Age group

 Adults

90/158 (56.96)

Reference

161/170 (94.71)

Reference

74/117 (63.25)

Reference

 Children

25/41 (60.98)

1.18 (0.58–2.38)

38/45 (84.44)

0.30 (0.11–0.87)*

17/24 (70.83)

1.41 (0.54–3.67)

Symptoms

 Symptomatic

96/166 (57.83)

Reference

162/177 (91.53)

Reference

69/105 (65.71)

Reference

 Asymptomatic

19/33 (57.58)

0.98 (0.46–2.11)

37/38 (97.37)

3.43 (0.44–26.76)

22/36 (61.11)

0.82 (0.37–1.79)

Year

 2019

31/64 (48.44)

Reference

70/74 (94.59)

Reference

43/68 (63.24)

Reference

 2020

84/135 (62.22)

1.75 (0.96–3.20)

129/141 (91.49)

0.61 (0.19–1.98)

48/73 (65.75)

1.12 (0.56–2.23)

  1. *p < 0.05