Table 3 Frequency of kdr allele in each Anopheles species from adult mosquito collection
Arms | Species | Baseline | Intrevention | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | Wild-type | Mutant | Frequency of R allele | n | Wild-type | Mutant | Frequency of R allele | ||||||||||
SS | L1014F | L1014S | Hetero duplex | SS | L1014F | L1014S | Hetero duplex | ||||||||||
RS | RR | RS | RR | RS | RR | RS | RR | ||||||||||
Treated | An. aconitus | 81 | 79 | 2 | – | – | – | – | 0.012 | 733 | 678 | 24 | 19 | 9 | 2 | 1 | 0.053 |
An. annularis | 21 | 13 | 2 | – | 5 | – | 1 | 0.214 | 37 | 21 | 2 | 1 | 8 | 2 | 3 | 0.297 | |
An. balabacensis | – | – | – | – | – | – | – | #NA | – | – | – | – | – | – | – | NA | |
An. barbirostris | 4 | 4 | – | – | – | – | – | 0.000 | 19 | 18 | – | 1 | – | – | – | 0.053 | |
An. flavirostris | 92 | 86 | 6 | – | – | – | – | 0.033 | 327 | 306 | 14 | 4 | 3 | – | – | 0.038 | |
An. indefinitus | – | – | – | – | – | – | – | NA | 4 | 4 | – | – | – | – | – | 0.000 | |
An. kochi | 2 | 2 | – | – | – | – | – | 0.000 | 33 | 30 | 1 | 2 | – | – | – | 0.076 | |
An. maculatus | 13 | 13 | – | – | – | – | – | 0.000 | 61 | 58 | 3 | – | – | – | – | 0.025 | |
An. subpictus | 2 | – | – | – | – | 2 | – | 1.000 | 6 | 3 | 1 | – | – | 1 | 1 | 0.417 | |
An. sundaicus | 157 | 154 | 2 | – | – | 1 | – | 0.013 | 19 | 18 | – | – | – | 1 | – | 0.053 | |
An. tesselatus | 11 | 7 | 2 | 2 | – | – | – | 0.273 | 53 | 26 | 12 | 11 | 1 | – | 3 | 0.387 | |
An. vagus | 40 | 39 | – | 1 | – | – | – | 0.025 | 94 | 83 | 3 | 2 | 2 | 2 | 2 | 0.090 | |
All Anopheles | 423 | 397 | 14 | 3 | 5 | 3 | 1 | 0.039 | 1386 | 1245 | 60 | 40 | 23 | 8 | 10 | 0.072 | |
Placebo | An. aconitus | 17 | 17 | – | – | – | – | – | 0.000 | 59 | 49 | 3 | 5 | 2 | – | – | 0.127 |
An. annularis | 85 | 66 | 2 | 2 | 14 | 1 | – | 0.129 | 138 | 84 | 10 | 4 | 33 | 6 | 1 | 0.236 | |
An. balabacensis | – | – | – | – | – | – | – | NA | 18 | 18 | – | – | – | – | – | 0.000 | |
An. barbirostris | 16 | 15 | 1 | – | – | – | – | 0.031 | 60 | 54 | 1 | 3 | – | – | 2 | 0.092 | |
An. flavirostris | 76 | 75 | – | – | – | – | 1 | 0.013 | 166 | 157 | 3 | 4 | 1 | – | 1 | 0.042 | |
An. indefinitus | – | – | – | – | – | – | – | NA | 8 | 3 | – | 2 | – | 2 | 1 | 0.625 | |
An. kochi | 64 | 61 | 2 | – | – | – | 1 | 0.031 | 223 | 197 | 10 | 8 | 4 | 4 | – | 0.085 | |
An. maculatus | 17 | 10 | 5 | 2 | – | – | – | 0.265 | 33 | 32 | – | – | 1 | – | – | 0.015 | |
An. subpictus | 3 | 2 | – | – | – | – | 1 | 0.333 | 55 | 16 | 2 | 6 | 4 | 10 | 17 | 0.655 | |
An. sundaicus | 27 | 24 | 1 | – | 2 | – | – | 0.056 | 12 | 12 | – | – | – | – | – | 0.000 | |
An. tesselatus | 43 | 20 | 8 | 14 | – | – | 1 | 0.442 | 240 | 79 | 43 | 106 | 3 | 1 | 8 | 0.575 | |
An. vagus | 119 | 112 | 2 | 3 | 2 | – | – | 0.042 | 232 | 195 | 6 | 4 | 1 | 9 | 17 | 0.144 | |
All Anopheles | 467 | 402 | 21 | 21 | 18 | 1 | 4 | 0.097 | 1244 | 896 | 78 | 142 | 49 | 32 | 47 | 0.191 | |