Drug/Site | Analysis | Hb D7 | Hb D14 | Hb D21 | Hb D28 | Hb D35 | Hb D42 |
---|---|---|---|---|---|---|---|
ALa | |||||||
 Anié | Mean increase | 0.29 | 0.88 | 1.02 | 1.22 | 1.23 | 1.31 |
95% CI | 0.03–0.55 | 0.58–1.19 | 0.72–1.32 | 0.90–1.53 | 0.90–1.57 | 0.95 to 1.67 | |
P-value |  < 0.04 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | |
 Kouvé | Mean increase | 0.05914 | 0.91 | 1.4811 | 1.71 | 1.74 | 1.84 |
95% CI | − 0.21 to 0.33 | 0.60 to 1.23 | 1.12 to 1.84 | 1.33 to 2.09 | 1.36 to 2.14 | 1.44 to 2.24 | |
P-value | 0.66 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | |
DPb | |||||||
 Anié | Mean increase | 0.46 | 1.14 | 1.57 | 1.65 | 1.76 | 1.82 |
95% CI | 0.10 to 0.81 | 0.80 to 1.48 | 1.22 to 1.93 | 1.27 to 2.04 | 1.36 to 2.15 | 1.46 to 2.18 | |
P-value |  < 0.02 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | |
 Kouvé | Mean decrease | − 0.3284 | 0.58 | 1.18 | 1.51 | 1.62 | 1.74 |
95% CI | − 0.59 to − 0.07 | 0.23 to 0.93 | 0.23 to 0.93 | 1.16 to 1.86 | 1.25 to 1.98 | 1.25 to 1.98 | |
P-value |  < 0.02 |  < 0.002 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |