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  1. Malaria is the leading cause of morbidity and mortality in Sudan. The entire population is at risk of contracting malaria to different levels. This study aimed to assess the effectiveness of communication for ...

    Authors: Yousif Mohammed Elmosaad, Magda Elhadi, Asif Khan, Elfatih Mohamed Malik and Ilias Mahmud
    Citation: Malaria Journal 2016 15:509
  2. Anti-malarial drug resistance continues to be a leading threat to malaria control efforts and calls for continued monitoring of waning efficacy of artemisinin-based combination therapy (ACT). Artesunate + sulf...

    Authors: Praveen K. Bharti, Man M. Shukla, Pascal Ringwald, Sri Krishna, Pushpendra P. Singh, Ajay Yadav, Sweta Mishra, Usha Gahlot, Jai P. Malaiya, Amit Kumar, Shambhu Prasad, Pradeep Baghel, Mohan Singh, Jaiprakash Vadadi, Mrigendra P. Singh, Maria Dorina G. Bustos…
    Citation: Malaria Journal 2016 15:498
  3. In malaria-endemic areas, the first exposure to malaria antigens often occurs in utero when the fetal immune system is poised towards the development of tolerance. Children exposed to placental malaria have an...

    Authors: Mary Prahl, Prasanna Jagannathan, Tara I. McIntyre, Ann Auma, Lila Farrington, Samuel Wamala, Mayimuna Nalubega, Kenneth Musinguzi, Kate Naluwu, Esther Sikyoma, Rachel Budker, Hilary Vance, Pamela Odorizzi, Patience Nayebare, John Ategeka, Abel Kakuru…
    Citation: Malaria Journal 2016 15:497
  4. The performance of different malaria rapid diagnostic tests (RDT) may be influenced by transmission intensity and by the length of time each test requires to become negative after treatment and patient’s recov...

    Authors: Francesco Grandesso, Carolyn Nabasumba, Dan Nyehangane, Anne-Laure Page, Mathieu Bastard, Martin De Smet, Yap Boum and Jean-François Etard
    Citation: Malaria Journal 2016 15:496
  5. A targeted malaria elimination project, including mass drug administrations (MDA) of dihydroartemisinin/piperaquine plus a single low dose primaquine is underway in villages along the Thailand Myanmar border. ...

    Authors: Ladda Kajeechiwa, May Myo Thwin, Paw Wah Shee, Nan Lin Yee, Elvina Elvina, Peapah Peapah, Kyawt Kyawt, Poe Thit Oo, William PoWah, Jacqueline Roger Min, Jacher Wiladphaingern, Lorenz von Seidlein, Suphak Nosten and Francois Nosten
    Citation: Malaria Journal 2016 15:494
  6. Emergence of high-grade sulfadoxine-pyrimethamine (SP) resistance in parts of Africa has led to growing concerns about the efficacy of intermittent preventive treatment of malaria during pregnancy (IPTp) with ...

    Authors: Silke Fernandes, Elisa Sicuri, Diawara Halimatou, James Akazili, Kalifa Boiang, Daniel Chandramohan, Sheikh Coulibaly, Sory Ibrahim Diawara, Kassoum Kayentao, Feiko ter Kuile, Pascal Magnussen, Harry Tagbor, John Williams, Arouna Woukeu, Matthew Cairns, Brian Greenwood…
    Citation: Malaria Journal 2016 15:493
  7. Strategies designed to advance towards malaria elimination rely on the detection and treatment of infections, rather than fever, and the interruption of malaria transmission between mosquitoes and humans. Mass...

    Authors: Vanderson S. Sampaio, Tatiana P. Beltrán, Kevin C. Kobylinski, Gisely C. Melo, José B. P. Lima, Sara G. M. Silva, Íria C. Rodriguez, Henrique Silveira, Maria G. V. B. Guerra, Quique Bassat, Paulo F. P. Pimenta, Marcus V. G. Lacerda and Wuelton M. Monteiro
    Citation: Malaria Journal 2016 15:491
  8. The serial interval is a fundamentally important quantity in infectious disease epidemiology that has numerous applications to inferring patterns of transmission from case data. Many of these applications are apr...

    Authors: John H. Huber, Geoffrey L. Johnston, Bryan Greenhouse, David L. Smith and T. Alex Perkins
    Citation: Malaria Journal 2016 15:490
  9. Knowledge of Anopheles resting habitats is needed to advance outdoor malaria vector control. This study presents a technique to map locations of resting habitats using high-resolution satellite imagery (world vie...

    Authors: Julius R. Dewald, Douglas O. Fuller, Günter C. Müller and John C. Beier
    Citation: Malaria Journal 2016 15:489
  10. A malaria eradication goal has been proposed, at the same time as a new global strategy and implementation framework. Countries are considering the strategies and tools that will enable progress towards malari...

    Authors: Cara Smith Gueye, Gretchen Newby, Jim Tulloch, Laurence Slutsker, Marcel Tanner and Roland D. Gosling
    Citation: Malaria Journal 2016 15:488
  11. Malaria, a disease caused by protozoan parasites of the genus Plasmodium and transmitted by female anopheline mosquitoes, is a major cause of morbidity, mortality and loss in productivity in humans. Baringo Count...

    Authors: Edna N. Mutua, Salome A. Bukachi, Bernard K. Bett, Benson A. Estambale and Isaac K. Nyamongo
    Citation: Malaria Journal 2016 15:486
  12. Current knowledge of human immunological responses to pregnancy-associated malaria-specific Plasmodium falciparum protein VAR2CSA concerns almost exclusively B cell-driven antibody-mediated activity. Knowledge o...

    Authors: Komi Gbédandé, Gilles Cottrell, Bertin Vianou, Samad Ibitokou, Aurax Fernando, Marita Troye-Blomberg, Ali Salanti, Kabirou Moutairou, Achille Massougbodji, Nicaise Tuikue Ndam, Philippe Deloron, Adrian J. F. Luty and Nadine Fievet
    Citation: Malaria Journal 2016 15:485
  13. Non-synonymous mutations in dhfr and dhps genes in Plasmodium vivax are associated with sulfadoxine–pyrimethamine (SP) resistance. The present study aimed to assess the prevalence of point mutations in P. vivax d...

    Authors: Naowarat Saralamba, Supatchara Nakeesathit, Mayfong Mayxay, Paul N. Newton, Lyda Osorio, Jung-Ryong Kim, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp and Mallika Imwong
    Citation: Malaria Journal 2016 15:484
  14. Malaria infections during pregnancy lead to sequestration of parasite infected red blood cells in the placenta. Placental infection can result in adverse outcomes for mothers and infants. Despite many studies,...

    Authors: Lauren M. Cohee, Linda Kalilani-Phiri, Patricia Mawindo, Sudhaunshu Joshi, Matthew Adams, Leo Kenefic, Christopher G. Jacob, Terrie E. Taylor and Miriam K. Laufer
    Citation: Malaria Journal 2016 15:483
  15. Sickle-cell trait (HbAS) reduces falciparum malaria risk and suppresses parasitaemia. Although several candidate mechanisms have been proposed, their epidemiological, clinical and experimental correlates have ...

    Authors: Seidina A. S. Diakité, Papa Alioune Ndour, Valentine Brousse, Frederick Gay, Camille Roussel, Sylvestre Biligui, Michaël Dussiot, Virginie Prendki, Tatiana M. Lopera-Mesa, Karim Traoré, Drissa Konaté, Saibou Doumbia, Jérôme Cros, Safi Dokmak, Rick M. Fairhurst, Mahamadou Diakité…
    Citation: Malaria Journal 2016 15:482
  16. Zanthoxylum heitzii (Rutaceae) (olon) is used in traditional medicine in Central and West Africa to treat malaria. To identify novel compounds with anti-parasitic activity and validate...

    Authors: Christopher Dean Goodman, Ingvild Austarheim, Vanessa Mollard, Bertin Mikolo, Karl Egil Malterud, Geoffrey I. McFadden and Helle Wangensteen
    Citation: Malaria Journal 2016 15:481

    The Erratum to this article has been published in Malaria Journal 2016 15:560

  17. As emergency response to the Ebola epidemic, the Government of Sierra Leone and its partners implemented a large-scale Mass Drug Administration (MDA) with artesunate–amodiaquine (ASAQ) covering >2.7 million pe...

    Authors: Maru Aregawi, Samuel J. Smith, Musa Sillah-Kanu, John Seppeh, Anitta R. Y. Kamara, Ryan O. Williams, John J. Aponte, Andrea Bosman and Pedro Alonso
    Citation: Malaria Journal 2016 15:480
  18. Artemisinin-based combination therapy (ACT) introduced in the mid-1990s has been recommended since 2005 by the World Health Organization as first-line treatment against Plasmodium falciparum in all endemic countr...

    Authors: Jean Baptiste Roseau, Bruno Pradines, Nicolas Paleiron, Serge Vedy, Marylin Madamet, Fabrice Simon and Emilie Javelle
    Citation: Malaria Journal 2016 15:479
  19. Cedrol, a sesquiterpene alcohol, is the first identified oviposition attractant for African malaria vectors. Finding the natural source of this compound might help to elucidate why Anopheles gambiae and Anopheles...

    Authors: Lynda K. Eneh, Hiromi Saijo, Anna-Karin Borg-Karlson, Jenny M. Lindh and Gunaratna Kuttuva Rajarao
    Citation: Malaria Journal 2016 15:478
  20. Malaria remains a major public health problem, with half the world population at risk of contracting malaria. The effects of Plasmodium vivax on prosperity and longevity have been highlighted in several recent cl...

    Authors: Dhelio Pereira, André Daher, Graziela Zanini, Ivan Maia, Lais Fonseca, Luciana Pitta, Rosilene Ruffato, Paola Marchesini and Cor Jesus Fontes
    Citation: Malaria Journal 2016 15:477
  21. Placental malaria caused by Plasmodium falciparum infection constitutes a major health problem manifesting as severe disease and anaemia in the mother, impaired fetal development, low birth weight or spontaneous ...

    Authors: Arnaud Chêne, Sophie Houard, Morten A. Nielsen, Sophia Hundt, Flavia D’Alessio, Sodiomon B. Sirima, Adrian J. F. Luty, Patrick Duffy, Odile Leroy, Benoit Gamain and Nicola K. Viebig
    Citation: Malaria Journal 2016 15:476
  22. Experience of seasonal malaria chemoprevention (SMC) is growing in the Sahel sub-region of Africa, though there remains insufficient evidence to recommend a standard deployment strategy. In 2012, a project was...

    Authors: Clare E. Strachan, Musa Kana, Sandrine Martin, John Dada, Naome Wandera, Madeleine Marasciulo, Helen Counihan, Maxwell Kolawole, Tanimu Babale, Prudence Hamade, Sylvia R. Meek and Ebenezer Baba
    Citation: Malaria Journal 2016 15:474
  23. The advent of whole-genome sequencing has generated increased interest in modelling the structure of strain mixture within clinical infections of Plasmodium falciparum The life cycle of the parasite implies that...

    Authors: John D. O’Brien, Lucas Amenga-Etego and Ruiqi Li
    Citation: Malaria Journal 2016 15:473
  24. Internally displaced persons (IDP) represent vulnerable populations whose public health conditions merit special attention. In the China–Myanmar border area, human movement and resettlements of IDP can influen...

    Authors: Guofa Zhou, Eugenia Lo, Daibin Zhong, Xiaoming Wang, Ying Wang, Sameer Malla, Ming-chieh Lee, Zhaoqing Yang, Liwang Cui and Guiyun Yan
    Citation: Malaria Journal 2016 15:471
  25. Parasite prevalence is a key metric used to quantify the burden of malaria and assess the impact of control strategies. Most published estimates of parasite prevalence are based on microscopy and likely undere...

    Authors: John Rek, Shereen Katrak, Hannah Obasi, Patience Nayebare, Agaba Katureebe, Elijah Kakande, Emmanuel Arinaitwe, Joaniter I. Nankabirwa, Prasanna Jagannathan, Chris Drakeley, Sarah G. Staedke, David L. Smith, Teun Bousema, Moses Kamya, Philip J. Rosenthal, Grant Dorsey…
    Citation: Malaria Journal 2016 15:470
  26. Ferroquine (SSR97193) is a candidate anti-malarial currently undergoing clinical trials for malaria. To better understand its pharmacokinetic (PK) and pharmacodynamic (PD) parameters the compound was tested in...

    Authors: James S. McCarthy, Thomas Rückle, Elhadj Djeriou, Cathy Cantalloube, Daniel Ter-Minassian, Mark Baker, Peter O’Rourke, Paul Griffin, Louise Marquart, Rob Hooft van Huijsduijnen and Jörg J. Möhrle
    Citation: Malaria Journal 2016 15:469
  27. As malaria transmission declines, it becomes more geographically focused and more likely due to asymptomatic and non-falciparum infections. To inform malaria elimination planning in the context of this changin...

    Authors: Herdiana Herdiana, Chris Cotter, Farah N. Coutrier, Iska Zarlinda, Brittany W. Zelman, Yusrifar Kharisma Tirta, Bryan Greenhouse, Roly D. Gosling, Peter Baker, Maxine Whittaker and Michelle S. Hsiang
    Citation: Malaria Journal 2016 15:468
  28. There has been some evidence to suggest that the addition of chloroquine (CQ) or quinine (QN) to 8-aminoquinoline (8-AQ) treatment regimens may increase the therapeutic efficacy of the 8-AQ and simultaneously ...

    Authors: Pius S. Fasinu, Babu L. Tekwani, Bharathi Avula, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, Yan-Hong Wang, Ikhlas A. Khan and Larry A. Walker
    Citation: Malaria Journal 2016 15:466
  29. Reliable quantification of mosquito host—seeking behaviours is required to determine the efficacy of vector control methods. For malaria, the gold standard approach remains the risky human landing catch (HLC)....

    Authors: Nicodem J. Govella, Deodatus F. Maliti, Amos T. Mlwale, John P. Masallu, Nosrat Mirzai, Paul C. D. Johnson, Heather M. Ferguson and Gerry F. Killeen
    Citation: Malaria Journal 2016 15:465
  30. Acute kidney injury (AKI) is a frequently encountered complication of imported Plasmodium falciparum infection. Markers of structural kidney damage have been found to detect AKI earlier than serum creatinine-base...

    Authors: Marlies E. van Wolfswinkel, Liese C. Koopmans, Dennis A. Hesselink, Ewout J. Hoorn, Rob Koelewijn, Jaap J. van Hellemond and Perry J. J. van Genderen
    Citation: Malaria Journal 2016 15:464
  31. An effective malaria transmission-blocking vaccine may play an important role in malaria elimination efforts, and a robust biological assay is essential for its development. The standard membrane-feeding assay...

    Authors: Kazutoyo Miura, Will J. R. Stone, Karin M. Koolen, Bingbing Deng, Luwen Zhou, Geert-Jan van Gemert, Emily Locke, Merribeth Morin, Teun Bousema, Robert W. Sauerwein, Carole A. Long and Koen J. Dechering
    Citation: Malaria Journal 2016 15:463
  32. Haemoglobinuria is an uncommon complication of severe malaria, reflecting acute intravascular haemolysis and potentially leading to acute kidney injury. It can occur early in the course of infection as a conse...

    Authors: Bridget E. Barber, Matthew J. Grigg, Timothy William, Tsin W. Yeo and Nicholas M. Anstey
    Citation: Malaria Journal 2016 15:462
  33. Malaria is a mosquito-borne infectious disease with diverse clinical manifestations caused by a parasitic protozoan of the genus Plasmodium. Complex inter-relationships between Mycoplasma species and Plasmodium p...

    Authors: Praveen Weeratunga, Gowri Rathnayake, Ahalya Sivashangar, Panduka Karunanayake, Ariaranee Gnanathasan and Thashi Chang
    Citation: Malaria Journal 2016 15:461
  34. Health clinics in rural Africa are typically resource-limited. As a result, many patients presenting with fever are treated with anti-malarial drugs based only on clinical presentation. This is a considerable ...

    Authors: Ria R. Ghai, Mary I. Thurber, Azza El Bakry, Colin A. Chapman and Tony L. Goldberg
    Citation: Malaria Journal 2016 15:460
  35. Following initiation of China’s National Malaria Elimination Action Plan in 2010, indigenous malaria infections in Jiangsu Province decreased significantly. Meanwhile imported Plasmodium infections have increased...

    Authors: Yuanyuan Cao, Weiming Wang, Yaobao Liu, Chris Cotter, Huayun Zhou, Guoding Zhu, Jianxia Tang, Feng Tang, Feng Lu, Sui Xu, Yaping Gu, Chao Zhang, Julin Li and Jun Cao
    Citation: Malaria Journal 2016 15:459
  36. Indoor residual spraying (IRS) is used as part of the integrated vector management strategy for the control of malaria in Lagos, Nigeria. The purpose of this study was to compare the malariometric indices of c...

    Authors: Babatunde A. Odugbemi, Kikelomo O. Wright, Adebayo T. Onajole, Yetunde A. Kuyinu, Olayinka O. Goodman, Tinuola O. Odugbemi and Olumuyiwa O. Odusanya
    Citation: Malaria Journal 2016 15:458
  37. Immunological characterization of potential blood-stage malaria antigens would be a valuable strategy in the development of an effective vaccine. Identifying B and CD4+ T cell epitopes will be important in unders...

    Authors: Aakanksha Kalra, Paushali Mukherjee and Virander S. Chauhan
    Citation: Malaria Journal 2016 15:457
  38. Malaria continues to be a major burden in the endemic regions of Kenya. Health outcomes associated with case management are dependent on the use of appropriate diagnostic methods. Rapid diagnostic tests (RDTs)...

    Authors: Elizabeth W. Wanja, Nickline Kuya, Collins Moranga, Mark Hickman, Jacob D. Johnson, Carolyne Moseti, Lalaine Anova, Bernhards Ogutu and Colin Ohrt
    Citation: Malaria Journal 2016 15:456
  39. Between 2009 and 2012, malaria cases diagnosed in a Médecins sans Frontières programme have increased fivefold in Baraka, South Kivu, Democratic Republic of the Congo (DRC). The cause of this increase is not k...

    Authors: Marit de Wit, Anna L. Funk, Krystel Moussally, David Aksanti Nkuba, Ruby Siddiqui, Karla Bil, Erwan Piriou, Aldert Bart, Patrick Bahizi Bizoza and Teun Bousema
    Citation: Malaria Journal 2016 15:455
  40. Despite the significant gains made globally in reducing the burden of malaria, the disease remains a major public health challenge, especially in sub-Saharan Africa (SSA) including Ghana. There is a significan...

    Authors: Justice Nonvignon, Genevieve Cecilia Aryeetey, Keziah L. Malm, Samuel Agyei Agyemang, Vivian N. A. Aubyn, Nana Yaw Peprah, Constance N. Bart-Plange and Moses Aikins
    Citation: Malaria Journal 2016 15:454
  41. The US Army designed artelinate/lysine salt (AL) to overcome the instability of sodium artesunate in aqueous solution (AS). To select the most efficacious artemisinin treatment, direct comparison was performed...

    Authors: Paktiya Teja-Isavadharm, Duangsuda Siriyanonda, Maneerat Rasameesoraj, Amporn Limsalakpeth, Nitima Chanarat, Natthasorn Komcharoen, Peter J. Weina, David L. Saunders, Montip Gettayacamin and R. Scott Miller
    Citation: Malaria Journal 2016 15:453
  42. Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compou...

    Authors: Sabina Dahlström Otienoburu, Oumou Maïga-Ascofaré, Birgit Schramm, Vincent Jullien, Joel J. Jones, Yah M. Zolia, Pascal Houzé, Elizabeth A. Ashley, Jean-René Kiechel, Philippe J. Guérin, Jacques Le Bras and Sandrine Houzé
    Citation: Malaria Journal 2016 15:452
  43. Sub-Saharan Africa (SSA) has embarked on a new era of dam building to improve food security and promote economic development. Nonetheless, the future impacts of dams on malaria transmission are poorly understo...

    Authors: Solomon Kibret, Jonathan Lautze, Matthew McCartney, Luxon Nhamo and G. Glenn Wilson
    Citation: Malaria Journal 2016 15:448
  44. Plasmodium knowlesi and Plasmodium cynomolgi are two malaria parasites naturally transmissible between humans and wild macaque through mosquito vectors, while Plasmodium inui can be ex...

    Authors: Xinjun Zhang, Khamisah Abdul Kadir, Leslie Fabiola Quintanilla-Zariñan, Jason Villano, Paul Houghton, Hongli Du, Balbir Singh and David Glenn Smith
    Citation: Malaria Journal 2016 15:450

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