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SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics

Population genetic analysis of malaria parasites requires high resolution genotyping tools that can accurately measure parasite diversity and relatedness and discriminate between populations within an endemic area. Fola and colleagues have developed a SNP barcode that captures the diversity of Plasmodium vivax populations of Papua New Guinea. This new genotyping tool measures diversity and population structure with greater resolution than the previously used microsatellite panel. The results demonstrate how SNP barcodes, validated against the local parasite population, can generate critical insights into transmission dynamics to inform malaria control and elimination.  

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