Skip to main content

Table 1 Estimated age of malaria resistance variants in years (assuming a 25-year generation length) and the selection coefficient (estimated or assumed), --- indicates no selection (neutrality) is assumed

From: Resistance to malaria in humans: the impact of strong, recent selection

Gene

 allele

Age

Selection coefficient

Reference

β -globin

   

 S

1,440

0.152

[34]

 C

2,810

0.06

[36]

 E

2,510

0.079

[39]

G6PD

   

 A-

6,360

0.044

[40]

 A-

1,000

0.25

[41]

 Med

3,330

0.034

[40]

 Mahidol

1,580

0.23

[42]

HLA-B

   

 B53

2,150

0.041

[6]

Duffy

   

 ES (null)

33,000

---

[49]

 ES (null)

10,000

---

[50]

Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us