Skip to main content
Figure 2 | Malaria Journal

Figure 2

From: Polysaccharides from the Chinese medicinal herb Achyranthes bidentata enhance anti-malarial immunity during Plasmodium yoelii 17XL infection in mice

Figure 2

The effects of ABPS pretreatment on immune responses during early Plasmodium yoelii 17XL (P. y 17XL) infection. Mice were injected i.p. with two different dosages of ABPS (10 mg/kg and 50 mg/kg) for consecutive 10 days prior to infection, and spleen lysates were prepared on days 0, 3 and 5 after infection. The control group (NC) received the same volume of physiological saline at the same time points. (A) Total number of splenocytes per mouse. (B) Levels of IFN-γ (C) Levels of TNF-α (D) Total number of F4/80+ macrophages. (E) Total number of CD36+ macrophages. (F) Concentration of NO2-. Values represent the mean with standard error (n = 3 mice per group). Results are representative of three independent experiments. Asterisk (*) indicates statistically significant difference (P < 0.05) between the control and ABPS pretreated groups of mice. Open, grey and black boxes indicate control group (NC), 10 mg/kg ABPS group (10 mg), and 50 mg/kg ABPS group (50 mg), respectively

Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us