WHO: World malaria report 2011. 2011, Geneva: World Health Organization
Google Scholar
Snow RW, Omumbo JA, Lowe B, Molyneux CS, Obiero JO, Palmer A, Weber MW, Pinder M, Nahlen B, Obonyo C, Newbold C, Gupta S, Marsh K: Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa. Lancet. 1997, 349: 1650-1654. 10.1016/S0140-6736(97)02038-2.
Article
CAS
PubMed
Google Scholar
Lamb TJ, Langhorne J: The severity of malarial anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently of the number of circulating parasites. MalarJ. 2008, 7: 68-10.1186/1475-2875-7-68.
Article
Google Scholar
Price RN, Simpson JA, Nosten F, Luxemburger C, Hkirjaroen L, ter Kuile F, Chongsuphajaisiddhi T, White NJ: Factors contributing to anemia after uncomplicated falciparum malaria. AmJTrop Med Hyg. 2001, 65: 614-622.
CAS
Google Scholar
Chang KH, Stevenson MM: Malarial anaemia: mechanisms and implications of insufficient erythropoiesis during blood-stage malaria. Int J Parasitol. 2004, 34: 1501-1516. 10.1016/j.ijpara.2004.10.008.
Article
CAS
PubMed
Google Scholar
Jakeman GN, Saul A, Hogarth WL, Collins WE: Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes. Parasitology. 1999, 119 (Pt 2): 127-133.
Article
PubMed
Google Scholar
Lamikanra AA, Brown D, Potocnik A, Casals-Pascual C, Langhorne J, Roberts DJ: Malarial anemia: of mice and men. Blood. 2007, 110: 18-28. 10.1182/blood-2006-09-018069.
Article
CAS
PubMed
Google Scholar
Dold C, Holland CV: Ascaris and ascariasis. Microbes Infect. 2011, 13: 632-637. 10.1016/j.micinf.2010.09.012.
Article
PubMed
Google Scholar
Cooper PJ, Chico ME, Sandoval C, Espinel I, Guevara A, Kennedy MW, Urban JF, Griffin GE, Nutman TB: Human infection with Ascaris lumbricoides is associated with a polarized cytokine response. J Infect Dis. 2000, 182: 1207-1213. 10.1086/315830.
Article
CAS
PubMed
Google Scholar
Turner JD, Faulkner H, Kamgno J, Cormont F, Van Snick J, Else KJ, Grencis RK, Behnke JM, Boussinesq M, Bradley JE: Th2 cytokines are associated with reduced worm burdens in a human intestinal helminth infection. J Infect Dis. 2003, 188: 1768-1775. 10.1086/379370.
Article
CAS
PubMed
Google Scholar
Geiger SM, Massara CL, Bethony J, Soboslay PT, Carvalho OS, Correa-Oliveira R: Cellular responses and cytokine profiles in Ascaris lumbricoides and Trichuris trichiura infected patients. Parasite Immunol. 2002, 24: 499-509. 10.1046/j.1365-3024.2002.00600.x.
Article
CAS
PubMed
Google Scholar
Figueiredo CA, Barreto ML, Rodrigues LC, Cooper PJ, Silva NB, Amorim LD, Alcantara-Neves NM: Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network. Infect Immun. 2010, 78: 3160-3167. 10.1128/IAI.01228-09.
Article
PubMed Central
CAS
PubMed
Google Scholar
Turner JD, Jackson JA, Faulkner H, Behnke J, Else KJ, Kamgno J, Boussinesq M, Bradley JE: Intensity of intestinal infection with multiple worm species is related to regulatory cytokine output and immune hyporesponsiveness. J Infect Dis. 2008, 197: 1204-1212. 10.1086/586717.
Article
CAS
PubMed
Google Scholar
Wammes LJ, Hamid F, Wiria AE, de Gier B, Sartono E, Maizels RM, Luty AJ, Fillie Y, Brice GT, Supali T, Smits HH, Yazdanbakhsh M: Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum. Eur J Immunol. 2010, 40: 437-442. 10.1002/eji.200939699.
Article
CAS
PubMed
Google Scholar
Hagel I, Cabrera M, Puccio F, Santaella C, Buvat E, Infante B, Zabala M, Cordero R, Di Prisco MC: Co-infection with Ascaris lumbricoides modulates protective immune responses against Giardia duodenalis in school Venezuelan rural children. Acta Trop. 2011, 117: 189-195. 10.1016/j.actatropica.2010.12.001.
Article
CAS
PubMed
Google Scholar
Brutus L, Watier L, Hanitrasoamampionona V, Razanatsoarilala H, Cot M: Confirmation of the protective effect of Ascaris lumbricoides on Plasmodium falciparum infection: results of a randomized trial in Madagascar. AmJTrop Med Hyg. 2007, 77: 1091-1095.
Google Scholar
Nacher M, Singhasivanon P, Traore B, Vannaphan S, Gay F, Chindanond D, Franetich JF, Mazier D, Looareesuwan S: Helminth infections are associated with protection from cerebral malaria and increased nitrogen derivatives concentrations in Thailand. AmJTrop Med Hyg. 2002, 66: 304-309.
CAS
Google Scholar
Nacher M, Singhasivanon P, Silachamroon U, Treeprasertsuk S, Vannaphan S, Traore B, Gay F, Looareesuwan S: Helminth infections are associated with protection from malaria-related acute renal failure and jaundice in Thailand. AmJTrop Med Hyg. 2001, 65: 834-836.
CAS
Google Scholar
Kirwan P, Asaolu SO, Molloy SF, Abiona TC, Jackson AL, Holland CV: Patterns of soil-transmitted helminth infection and impact of four-monthly albendazole treatments in preschool children from semi-urban communities in Nigeria: a double-blind placebo-controlled randomised trial. BMC Infect Dis. 2009, 9: 20-10.1186/1471-2334-9-20.
Article
PubMed Central
PubMed
Google Scholar
Kirwan P, Jackson AL, Asaolu SO, Molloy SF, Abiona TC, Bruce MC, Ranford-Cartwright L, SM ON, Holland CV: Impact of repeated four-monthly anthelmintic treatment on Plasmodium infection in preschool children: a double-blind placebo-controlled randomized trial. BMC Infect Dis. 2010, 10: 277-10.1186/1471-2334-10-277.
Article
PubMed Central
PubMed
Google Scholar
WHO:Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System. 2011, Geneva: World Health Organization,
Google Scholar
Smith JL, Brooker S: Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review. Trop Med Int Health. 2010, 15: 776-795. 10.1111/j.1365-3156.2010.02542.x.
Article
PubMed Central
PubMed
Google Scholar
Carneiro I, Roca-Feltrer A, Griffin JT, Smith L, Tanner M, Schellenberg JA, Greenwood B, Schellenberg D: Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: a systematic review and pooled analysis. PLoS One. 2010, 5: e8988-10.1371/journal.pone.0008988.
Article
PubMed Central
PubMed
Google Scholar
Tshikuka JG, Scott ME, Gray-Donald K, Kalumba ON: Multiple infection with Plasmodium and helminths in communities of low and relatively high socio-economic status. Ann Trop Med Parasitol. 1996, 90: 277-293.
CAS
PubMed
Google Scholar
Worrall E, Basu S, Hanson K: Is malaria a disease of poverty? A review of the literature. Trop Med Int Health. 2005, 10: 1047-1059. 10.1111/j.1365-3156.2005.01476.x.
Article
CAS
PubMed
Google Scholar
Green HK, Sousa-Figueiredo JC, Basanez MG, Betson M, Kabatereine NB, Fenwick A, Stothard JR: Anaemia in Ugandan preschool-aged children: the relative contribution of intestinal parasites and malaria. Parasitology. 2011, 138: 1534-1545. 10.1017/S0031182011001016.
Article
PubMed
Google Scholar
Magalhaes RJS, Clements ACA: Mapping the Risk of anaemia in preschool-age children: the contribution of malnutrition, malaria, and helminth infections in West Africa. PLoS Med. 2011, 8: e1000438-10.1371/journal.pmed.1000438.
Article
PubMed
Google Scholar
Anah MU, Ikpeme OE, Etuk IS, Yong KE, Ibanga I, Asuquo BE: Worm infestation and anaemia among pre-school children of peasant farmers in Calabar, Nigeria. Niger J Clin Pract. 2008, 11: 220-224.
CAS
PubMed
Google Scholar
Melo GC, Reyes-Lecca RC, Vitor-Silva S, Monteiro WM, Martins M, Benzecry SG, Alecrim MG, Lacerda MV: Concurrent helminthic infection protects schoolchildren with Plasmodium vivax from anemia. PLoS One. 2010, 5: e11206-10.1371/journal.pone.0011206.
Article
PubMed Central
PubMed
Google Scholar
Nkuo-Akenji TK, Chi PC, Cho JF, Ndamukong KK, Sumbele I: Malaria and helminth co-infection in children living in a malaria endemic setting of mount Cameroon and predictors of anemia. J Parasitol. 2006, 92: 1191-1195. 10.1645/GE-895R.1.
Article
PubMed
Google Scholar
Stoltzfus RJ, Chwaya HM, Montresor A, Albonico M, Savioli L, Tielsch JM: Malaria, hookworms and recent fever are related to anemia and iron status indicators in 0- to 5-y old Zanzibari children and these relationships change with age. J Nutr. 2000, 130: 1724-1733.
CAS
PubMed
Google Scholar
Dufour C, Corcione A, Svahn J, Haupt R, Poggi V, Beka’ssy AN, Scime R, Pistorio A, Pistoia V: TNF-α and IFN-γ are overexpressed in the bone marrow of Fanconi anemia patients and TNF-α suppresses erythropoiesis in vitro. Blood. 2003, 102: 2053-2059. 10.1182/blood-2003-01-0114.
Article
CAS
PubMed
Google Scholar
McDevitt MA, Xie J, Shanmugasundaram G, Griffith J, Liu A, McDonald C, Thuma P, Gordeuk VR, Metz CN, Mitchell R, Keefer J, David J, Leng L, Bucala R: A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia. J Exp Med. 2006, 203: 1185-1196. 10.1084/jem.20052398.
Article
PubMed Central
CAS
PubMed
Google Scholar
Malaguarnera L, Imbesi RM, Pignatelli S, Simpore J, Malaguarnera M, Musumeci S: Increased levels of interleukin-12 in Plasmodium falciparum malaria: correlation with the severity of disease. Parasite Immunol. 2002, 24: 387-389. 10.1046/j.1365-3024.2002.00478.x.
Article
CAS
PubMed
Google Scholar
Mohan K, Stevenson MM: Interleukin-12 corrects severe anemia during blood-stage Plasmodium chabaudi AS in susceptible A/J mice. Exp Hematol. 1998, 26: 45-52.
CAS
PubMed
Google Scholar
Burgmann H, Looareesuwan S, Kapiotis S, Viravan C, Vanijanonta S, Hollenstein U, Wiesinger E, Presterl E, Winkler S, Graninger W: Serum levels of erythropoietin in acute Plasmodium falciparum malaria. AmJTrop Med Hyg. 1996, 54: 280-283.
CAS
Google Scholar
el Hassan AM, Saeed AM, Fandrey J, Jelkmann W: Decreased erythropoietin response in Plasmodium falciparum malaria-associated anaemia. Eur J Haematol. 1997, 59: 299-304.
Article
CAS
PubMed
Google Scholar
Jelkmann W: Proinflammatory cytokines lowering erythropoietin production. J Interferon Cytokine Res. 1998, 18: 555-559. 10.1089/jir.1998.18.555.
Article
CAS
PubMed
Google Scholar
Chang KH, Tam M, Stevenson MM: Modulation of the course and outcome of blood-stage malaria by erythropoietin-induced reticulocytosis. J Infect Dis. 2004, 189: 735-743. 10.1086/381458.
Article
PubMed
Google Scholar
Chang KH, Tam M, Stevenson MM: Inappropriately low reticulocytosis in severe malarial anemia correlates with suppression in the development of late erythroid precursors. Blood. 2004, 103: 3727-3735. 10.1182/blood-2003-08-2887.
Article
CAS
PubMed
Google Scholar
Othoro C, Lal AA, Nahlen B, Koech D, Orago AS, Udhayakumar V: A low interleukin-10 tumor necrosis factor-α ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya. J Infect Dis. 1999, 179: 279-282. 10.1086/314548.
Article
CAS
PubMed
Google Scholar
Walther M, Jeffries D, Finney OC, Njie M, Ebonyi A, Deininger S, Lawrence E, Ngwa-Amambua A, Jayasooriya S, Cheeseman IH, Gomez-Escobar N, Okebe J, Conway DJ, Riley EM: Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria. PLoS Pathog. 2009, 5: e1000364-10.1371/journal.ppat.1000364.
Article
PubMed Central
PubMed
Google Scholar
Walther M, Tongren JE, Andrews L, Korbel D, King E, Fletcher H, Andersen RF, Bejon P, Thompson F, Dunachie SJ, Edele F, de Souza JB, Sinden RE, Gilbert SC, Riley EM, Hill AV: pregulation of TGF-β, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity. 2005, 23: 287-296. 10.1016/j.immuni.2005.08.006.
Article
CAS
PubMed
Google Scholar
Couper KN, Blount DG, Wilson MS, Hafalla JC, Belkaid Y, Kamanaka M, Flavell RA, de Souza JB, Riley EM: IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathog. 2008, 4: e1000004-10.1371/journal.ppat.1000004.
Article
PubMed Central
PubMed
Google Scholar
Rosario AP Fd, Lamb T, Spence P, Stephens R, Lang A, Roers A, Muller W, O’Garra A, Langhorne J: IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J Immunol. 2012, 188: 1178-1190. 10.4049/jimmunol.1102755.
Article
Google Scholar
Li C, Sanni LA, Omer F, Riley E, Langhorne J: Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies. Infect Immun. 2003, 71: 4850-4856. 10.1128/IAI.71.9.4850-4856.2003.
Article
PubMed Central
CAS
PubMed
Google Scholar
Omer FM, Riley EM: Transforming growth factor β production is inversely correlated with severity of murine malaria infection. J Exp Med. 1998, 188: 39-48. 10.1084/jem.188.1.39.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ojurongbe O, Adegbayi AM, Bolaji OS, Akindele AA, Adefioye OA, Adeyeba OA: Asymptomatic falciparum malaria and intestinal helminths co-infection among school children in Osogbo, Nigeria. J Res Med Sci. 2011, 16: 680-686.
PubMed Central
PubMed
Google Scholar
Leung AK, Chan KW: Iron deficiency anemia. Adv Pediatr. 2001, 48: 385-408.
CAS
PubMed
Google Scholar
Odunvbun ME, Okolo AA, Rahimy CM: Newborn screening for sickle cell disease in a Nigerian hospital. Public Health. 2008, 122: 1111-1116. 10.1016/j.puhe.2008.01.008.
Article
CAS
PubMed
Google Scholar
Akinyanju OO: A profile of sickle cell disease in Nigeria. Ann N Y Acad Sci. 1989, 565: 126-136. 10.1111/j.1749-6632.1989.tb24159.x.
Article
CAS
PubMed
Google Scholar
Taylor SM, Parobek CM, Fairhurst RM: Haemoglobinopathies and the clinical epidemiology of malaria: a systematic review and meta-analysis. Lancet Infect Dis. 2012, 12: 457-468. 10.1016/S1473-3099(12)70055-5.
Article
PubMed Central
PubMed
Google Scholar
Onankpa B, Airede L, Paul I, Dorcas I: Pattern of pediatric HIV/AIDS: a five-year experience in a tertiary hospital. J Natl Med Assoc. 2008, 100: 821-825.
PubMed
Google Scholar
Okechukwu AA, Okechukwu OI: Prevalence of paediatric HIV infection in Federal Capital Territory, Abuja. Niger J Med. 2011, 20: 409-413.
CAS
PubMed
Google Scholar