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Table 2 Clinical details on patient B (Isolate MAL-1) throughout his hospital stay

From: Acute respiratory distress syndrome and acute renal failure from Plasmodium ovale infection with fatal outcome

Day

BP (mmHg)

Hb (g/dL)

Plt (×103/μl)

TSB (μmol/L)

AST (IU/L)

ALT (IU/L)

SCr (μmol/L)

Blood bacteriological & fungal culture

Anti-malarials

Antibiotics

Additional notes

1

102/55

12.4

65

16

47

39

100

N/A

N/A

N/A

PR 60 BPM; SPO2 97% RA; loss of appetite; Lungs: clear

2

92/52

N/A

N/A

N/A

N/A

N/A

107

N/A

Chloroquine

N/A

PR 70 BPM; Lungs: clear;

Primaquine

Dengue IgM negative

3

118/66

N/A

107

13

88

71

112

N/A

Chloroquine

N/A

PR 70 BPM; SPO2 98% RA;

Primaquine

Lungs: minimal basal crepitations

4

106/60

10.5

120

13

50

90

101

Negative

Artesunate

Ceftriaxone

PR 66 BPM; Haemoptysis, epistaxis, shortness of breath; CXR: bilateral haziness

Quinine

5

115/56

11.2

170

8

56

62

114

N/A

Artesunate

Ceftriaxone

Blood smear: negative for malaria parasites; Transferred to ICU

6

104/50

9.4

183

6

58

43

139

Negative

Artesunate

Tazocin®

Blood smear: negative for malaria

7

95/56

10.3

197

9

46

42

215

Negative

Artesunate

Tazocin®

Blood smear: negative for malaria

8

102/70

9.4

178

8

88

43

291

 

Artesunate

Tazocin®

Blood smear: negative for malaria; respiratory acidosis

Primaquine

9

143/64

9.0

184

7

49

39

297

Negative

Artesunate

Tazocin®

Blood smear: negative for malaria

10

170/60

8.5

199

10

54

48

316

N/A

Artesunate

Tazocin®

Blood smear: negative for malaria

11

165/68

8.1

231

8

99

81

301

N/A

N/A

Tazocin®

Ferritin blood test: 2,118 ng/ml

12

200/78

8.1

288

13

128

148

309

Negative

N/A

Vancomycin

 

Imipenem

13

160/60

6.8

311

16

137

190

392

N/A

N/A

Vancomycin

Hemolysis screening: negative;

Imipenem

CXR: worsening

14

170/63

9.1

265

13

47

106

408

N/A

N/A

Vancomycin

 

Imipenem

15

135/51

9.5

270

22

65

74

472

Positive for Enterobacter cloacae

N/A

Vancomycin

Rigours; acidosis (resp. & met.)

Imipenem

ABG: pH 7.128; pCO2 59.5 mmHg;

SLED 4 hours

16

111/45

9.1

225

19

43

51

413

N/A

N/A

Vancomycin

CVVHD

Imipenem

17

134/57

7.5

179

29

109

65

424

N/A

N/A

Vancomycin

Seizures; SLED 8 hours

Meropenem

18

135/55

7.3

178

30

38

40

320

N/A

N/A

Meropenem

Gentle HD 4 hours

19

130/56

9.0

204

34

40

30

404

N/A

N/A

Meropenem

Gentle HD 4 hours

20

147/61

8.6

207

25

43

26

403

N/A

N/A

Meropenem

Severe resp. acidosis; met. acidosis; gentle HD 4 hours

21

140/54

N/A

N/A

N/A

N/A

N/A

427

N/A

N/A

Meropenem

Gentle HD 3 hours

22

102/48

9.3

166

39

296

119

401

N/A

N/A

Meropenem

Worsening hypoxia; hypotensive; Gentle HD 6 hours

23

N/A

N/A

N/A

22

136

109

314

N/A

N/A

N/A

Asystole; death

  1. N/A = not available; BP = blood pressure; Hb = haemoglobin; Plt = platelet; TSB = total serum bilirubin; AST = aspartate aminotransferase; ALT = alanine aminotransferase; SCr = serum creatinine; BP = blood pressure; BPM = beats per minute; PR = pulse rate; SPO2 = blood oxygen saturation; RA = room air; IgM = immunoglobulin M; CXR = chest X-ray; ICU = intensive care unit; resp. = respiratory; met. = metabolic; ABG = arterial blood gas; pCO2 = partial pressure of carbon dioxide; SLED = sustained low efficiency dialysis; CVVHD = continuous veno-venous haemodialysis; HD = haemodialysis.
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Malaria Journal

ISSN: 1475-2875

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