From: Susceptibility of human Plasmodium knowlesi infections to anti-malarials
Drug | IC50values (nM) for P. knowlesi isolates (maturation assay)a | IC50values (nM) for P. knowlesi H strain ( p LDH assay)b |
---|---|---|
Mefloquine | 26 (± 3.1) | 25 (7.4 to 81)c |
Chloroquine | 23 (± 4.8) | 3.2 (2.2 to 4.7) |
Artemisinin | 2.1 (± 0.99) | 0.80 (0.35 to 1.9)c |
Artemether | 0.90 (± 0.19) | 0.84 (0.34 to 2.1)c |
Artesunate | 0.90 (± 0.12) | 2.0 (0.93 to 4.2)c |
DHA | 1.6 (± 0.92) | 0.79 (0.62 to 1.0) |