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Efficacy of Lagenidium giganteum (Couch) metabolites for control Anopheles stephensi (Liston) a malaria vector
© Singh and Prakash; licensee BioMed Central Ltd. 2010
- Published: 20 October 2010
- Malaria Transmission
- Malaria Vector
- Flash Chromatography
- Mosquito Control
Present study shows a high potential utility of fungal metabolites for complementing existing adult mosquito control measures. This approach demonstrates that the fugal metabolites have potential as a new strategy for vector control. It could be successful tool for controlling malaria vector in tropical countries with more community trials. Mosquitoes that are resistant to insecticides remain susceptible to fungal infection (Knols et al. 2010). Recently metabolites of F. oxysporum show significant pathogenicity against the larvae of An. stephensi in laboratory (Prakash et al. 2010). Regardless, the use of fungi L. giganteum to control population of An. stephensi mosquitoes clearly offers significant promise as a novel biologically based strategy to be integrated with other control measures to reduce global rate of malaria transmission. Also Scholte et al. (2005) have used fungal spores as adulticidal to control vector population in African villages, so fungal metabolites can be used as novel liquid adulticide.
We thank Prof. V.G. Das, Director, Dayalbagh Educational Institute, for his encouragements. We also thankful to the Department of Science and Technology for the financial support (DST, C-24/ Soam Prakash) to conduct the research and to DST - FIST program (2003-2008) for providing laboratory facilities. G. Singh is indebted to University Grants Commission, New Delhi, for an award of Post Doctoral Fellowship (2009-2011).
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