Fig. 4
From: Exploring anti-malarial potential of FDA approved drugs: an in silico approach
Targeting pfLDH. a Surface representation of crystal structure of pfLDH bound with its native substrate NADH, represented as sticks, is shown (PDB:1LDG). b Surface representation of crystal structure of pfLDH with docked nitrofural, in sticks, is shown. The details of the residues of pfLDH involved in interaction with its native substrate are illustrated in c and with the nitrofural in d. For convenience, only those residues are shown in stick representation which are common to binding substrate and the predicted drug