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Fig. 4 | Malaria Journal

Fig. 4

From: Network-driven analysis of human–Plasmodium falciparum interactome: processes for malaria drug discovery and extracting in silico targets

Fig. 4Fig. 4

A Functional interactions between C6KTD2 and C6KTB7 subnetwork in the unified host–pathogen functional network. The shared host proteins (yellow nodes) are involved in protein ubiquitination, positive regulation of cell apoptotic process, signal transduction, regulatory processes, and histone methylation. B Predicted shortest path network that could influence resistance and parasite adaptiveness between C6KTB7 (green node) and O00206 (bottom sky blue node) via co–targets (central sky blue nodes) in the host–pathogen network. C Predicted shortest path network that could influence resistance and parasite adaptiveness between C6KTD2 (green node) and O00206 (bottom sky blue node) via mediators (central sky blue nodes) in the host–pathogen network

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Malaria Journal

ISSN: 1475-2875

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