Fig. 3
From: Severe malaria
Approximate age relationships for the major clinical manifestations of severe falciparum malaria in relation to the intensity of transmission [53]. Holoendemic in this illustration approximates to a sustained entomological inoculation rate > 10 per year or a parasite rate (prevalence) in children of 0.5, and hypoendemic refers to an average entomological inoculation rate ≤ 1 year