Volume 8 Supplement 2

Development of the sterile insect technique for African malaria vectors


Edited by Mark Q Benedict, Alan S Robinson and Bart GJ Knols

This supplement is dedicated to Prof. Chris Curtis (1939-2008) of the London School of Hygiene and Tropical Medicine. His scientific efforts to control vector-borne diseases continually focused on maximizing humanitarian outcomes. Publication of this supplement was made possible by generous support from the International Atomic Energy Agency (IAEA).

  1. Review

    Conceptual framework and rationale

    The sterile insect technique (SIT) has been shown to be an effective and sustainable genetic approach to control populations of selected major pest insects, when part of area-wide integrated pest management (A...

    Alan S Robinson, Bart GJ Knols, Gabriella Voigt and Jorge Hendrichs

    Malaria Journal 2009 8(Suppl 2):S1

    Published on: 16 November 2009

  2. Review

    Ethical, legal and social aspects of the approach in Sudan

    The global malaria situation, especially in Africa, and the problems frequently encountered in chemical control of vectors such as insecticide resistance, emphasize the urgency of research, development and imp...

    Badria B El Sayed, Colin A Malcolm, Ahmed Babiker, Elfatih M Malik, Mohammed AH El Tayeb, Nageeb S Saeed, Abdel Hameed D Nugud and Bart GJ Knols

    Malaria Journal 2009 8(Suppl 2):S3

    Published on: 16 November 2009

  3. Review

    Colonisation and mass rearing: learning from others

    Mosquitoes, just as other insects produced for the sterile insect technique (SIT), are subjected to several unnatural processes including laboratory colonisation and large-scale factory production. After these...

    Mark Q Benedict, Bart GJ Knols, Hervé C Bossin, Paul I Howell, Eric Mialhe, Carlos Caceres and Alan S Robinson

    Malaria Journal 2009 8(Suppl 2):S4

    Published on: 16 November 2009

  4. Review

    Sex separation strategies: past experience and new approaches

    The success of the sterile insect technique (SIT) and other genetic strategies designed to eliminate large populations of insects relies on the efficient inundative releases of competitive, sterile males into ...

    Philippos A Papathanos, Hervé C Bossin, Mark Q Benedict, Flaminia Catteruccia, Colin A Malcolm, Luke Alphey and Andrea Crisanti

    Malaria Journal 2009 8(Suppl 2):S5

    Published on: 16 November 2009

  5. Review

    Radiation biology of mosquitoes

    There is currently renewed interest in assessing the feasibility of the sterile insect technique (SIT) to control African malaria vectors in designated areas. The SIT relies on the sterilization of males befor...

    Michelle EH Helinski, Andrew G Parker and Bart GJ Knols

    Malaria Journal 2009 8(Suppl 2):S6

    Published on: 16 November 2009

  6. Review

    Transgenic technologies to induce sterility

    The last few years have witnessed a considerable expansion in the number of tools available to perform molecular and genetic studies on the genome of Anopheles mosquitoes, the vectors of human malaria. As a conse...

    Flaminia Catteruccia, Andrea Crisanti and Ernst A Wimmer

    Malaria Journal 2009 8(Suppl 2):S7

    Published on: 16 November 2009

  7. Review

    Male mating biology

    Before sterile mass-reared mosquitoes are released in an attempt to control local populations, many facets of male mating biology need to be elucidated. Large knowledge gaps exist in how both sexes meet in spa...

    Paul I Howell and Bart GJ Knols

    Malaria Journal 2009 8(Suppl 2):S8

    Published on: 16 November 2009

  8. Review

    Field site selection: getting it right first time around

    The selection of suitable field sites for integrated control of Anopheles mosquitoes using the sterile insect technique (SIT) requires consideration of the full gamut of factors facing most proposed control strat...

    Colin A Malcolm, Badria El Sayed, Ahmed Babiker, Romain Girod, Didier Fontenille, Bart GJ Knols, Abdel Hameed Nugud and Mark Q Benedict

    Malaria Journal 2009 8(Suppl 2):S9

    Published on: 16 November 2009

  9. Epilogue

    SIT for African malaria vectors: Epilogue

    As a result of increased support and the diligent application of new and conventional anti-malaria tools, significant reductions in malaria transmission are being accomplished. Historical and current evolution...

    Harold Townson

    Malaria Journal 2009 8(Suppl 2):S10

    Published on: 16 November 2009